General Principles of Tumor Immunotherapy (eBook, PDF)

Basic and Clinical Applications of Tumor Immunology
Redaktion: Kaufman, Howard L.; Wolchok, Jedd D.

• Format: PDF

Produktbeschreibung

This book brings together the world's leading authorities on tumor immunology. This book describes the basic immunology principles that form the foundation of understanding how the immune system recognizes and rejects tumor cells. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated.

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Produktdetails

• Verlag: Springer Netherlands
• Seitenzahl: 503
• Erscheinungstermin: 12. Oktober 2007
• Englisch
• ISBN-13: 9781402060878
• Artikelnr.: 37342381

Autorenporträt

Howard L. Kaufman, Columbia University, New York, NY, USA / Jedd D. Wolchok, Memorial Sloan Kettering Cancer Center, New York, NY, USA

Inhaltsangabe

General Principles of Tumor Immunology.- A Perspective on Cancer Immunology and Immunotherapy.- Tumor Antigens.- T Cells and Antigen Recognition.- The Role of Natural Killer T cells in Tumor Immunity.- Immunomodulatory Molecules of the Immune System.- HLA Class I Antigen Abnormalities in Tumors.- The Local Tumor Microenvironment.- Tumor Vaccines.- Peptide and Protein Vaccines for Cancer.- DNA Vaccines Against Cancer.- Recombinant Viral and Bacterial Vaccines.- Dendritic Cell Vaccines.- Whole Cell Vaccines.- Carbohydrate Vaccines Against Cancer.- Passive Immunotherapy Approaches.- Monoclonal Antibody Therapy of Cancer.- Adoptive Cellular Therapy for the Treatment of Cancer.- Checkpoint Blockade and Combinatorial Immunotherapies.- Clinical Tumor Immunotherapy.- General Approaches to Measuring Immune Responses.- Interferon Therapy.- High Dose Interleukin-2 Therapy.- Monoclonal Antibodies in Cancer Therapy.- Unmasking tumor cell immunogenicity by chemotherapy: implications for therapy.