Genomic Instability and Immortality in Cancer (eBook, PDF)

Redaktion: Mihich, Enrico; Hartwell, Leland

• Format: PDF

Produktbeschreibung

Proceedings of the Eighth Annual Pezcoller Symposium held in Trento, Italy, June 17-19, 1996

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Produktdetails

• Verlag: Springer New York
• Seitenzahl: 251
• Erscheinungstermin: 6. Dezember 2012
• Englisch
• ISBN-13: 9781461553656
• Artikelnr.: 43983022

Inhaltsangabe

1. Telomeres and Cell Division in Drosophila melanogaster.- 2. A Molecular Cytogenetic View of Chromosomal Heterogeneity in Solid Tumors.- 3. Cell Cycle Control of Genetic Stability.- 4. Aneuploidy and Heterogeneity Mechanisms in Human Colorectal Tumor Progression.- 5. p53-Dependent Signaling in Response to DNA Damage or Arrest of DNA Synthesis and its Role in Cell Cycle Control.- 6. Recombining DNA Damage Repair, Basal Transcription, and Human Syndromes.- 7. Telomere Length Regulation by the Pif1 DNA Helicase.- 8. Consequences of Mutations that Alter Telomeres in the Yeast K. lactis.- 9. Regulation of Telomere Length in Mammalian Cells.- 10. The DNA Damage Checkpoint.- 11. A Eukaryotic Cell Cycle.- 12. The Integration of Signalling Pathways in Mammalian Cells.- 13. Antitumor Drugs and Yeast Cell Cycle Checkpoints.- 14. Neoplastic Progression in Barrett's Esophagus.- 15. E2F-1 Degradation by the Ubiquitin-Proteasome Pathway.- 16. Cdk4-Cyclin D1 and Cdk2-Cyclin E/A Phosphorylate Different Sites in the RB Protein.- 17. Cell Cycle Regulatory Proteins as Targets of Oncogenic Events.