Green Approaches in Medicinal Chemistry for Sustainable Drug Design (eBook, ePUB)

Applications
Redaktion: Banik, Bimal

• Format: ePub

Produktbeschreibung

Extensive experimentation and high failure rates are a well-recognized downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry 2e reveals how medicinal chemistry can play a direct role in addressing this issue.

After providing essential context to the growth of green chemistry in relation to drug discovery, the book goes on to identify a broad range of practical techniques and useful insights, revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process.

Drawing on the knowledge of a global team of experts, Sustainable and Green Approaches in Medicinal Chemistry, Second Edition encourages the growth of green medicinal chemistry, and supports medicinal chemists, drug discovery researchers, pharmacologists and all those in related fields across both academia and industry in integrating these approaches into their own work.

This second volume of the second edition includes the development of nanoparticles and nanocomposites, as well as the application of ultrasound and microwave-induced methods; studies solventless synthesis; defines the role of steroids; studies reactions in aqueous solution; identifies enzyme-mediated reactions; investigates ionic liquids and deep eutectic solvents; explores natural products; investigates solid supports; realizes the effects of salts; focuses on combinatorial chemistry; develops one-pot methods; analyzes multi-component reactions; investigates dipole moment values; and examines computer-assisted methods.

• Highlights the need for adoption of sustainable and green chemistry pathways in drug development
• Reveals risk factors associated with the drug development process and the ways sustainable approaches can help address these
• Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 600
• Erscheinungstermin: 31. Mai 2024
• Englisch
• ISBN-13: 9780443161674
• Artikelnr.: 70882838

Inhaltsangabe

Chemical Catalysis
1. Green Metal-Catalyzed Reactions Under Sustainable Conditions Towards
Medicinally Potent Biomolecules
2. Graphene Oxide and Modified Graphene Oxide-Mediated Synthesis of
Medicinally Active Compounds
3. Organocatalytic Cycloaddition Reaction: A Gateway for Molecular
Complexity
Biocatalysis
4. Baker's Yeast-Induced Synthesis of Medicinally Important Compounds
5. New Methods for the Manufacturing of Pharmaceuticals and Their
Intermediates Using Lipase
Green Solvents
6. Green Synthesis of Biologically Active Pyrroles and Related Substrates
via C-H Bond Functionalization
7. Ionic Liquids in Pharmaceutics and Bioanalytics
8. Synthesis of Bioactive Heterocyclic Compounds Using Green Solvents
9. Reactions in Water: Synthesis of Biologically Active Compounds
Green Chemistry
10. Sustainable Green Technologies for Synthesis of Potential Drugs
Targeted towards Tropical Diseases
11. Clay-Mediated Synthesis of Biologically Active Molecules: Green and
Sustainable Approaches
12. The Role of Ionic Liquid in Medicinal Chemistry
Medicinal Chemistry
13. Green Chemistry for the Synthesis of Sulfur containing Compounds with
Medicinal Properties
14. Sustainable green approaches for synthesis of bio-active flavonoids as
cardio-protective and anticancer drug agents
15. Polysaccharide-derived hydrogels: An approach towards cancer
16. Environmental Benign Pathways for the Synthesis of Medicinally Relevant
Heterocycles
17. Utilization of medicinally important plants as antidiabetic medicines
in a sustainable manner
18. One-Pot Synthesis of Biologically Active Oxazole, Iso-oxazole, and
Pyranopyazoles-An Overview
19. Green synthesis of Organometallic Compounds and their Medicinal aspects
20. Biologically active macrocycles in medicine
21. Green Synthesis and Biological Evaluation of Anticancer Drugs
22. Green Chemistry and Synthetic Approaches in the Development of
Antidepressant and Antipsychotic agents
23. Organocatalyzed multi-component synthesis of densely functionalized
bioactive pyridine derivatives
24. Multicomponent reaction strategy to heterocyclic compounds in
anticancer drug design
25. Recent Advances in Asymmetric Synthesis of ß-Lactams