Growth Hormone Deficiency (eBook, PDF)

Physiology and Clinical Management
Redaktion: Cohen, Laurie E.

• Format: PDF

Produktbeschreibung

Providing the most current information on the function of human growth hormone (GH) and the consequences of its deficiency, this practical yet comprehensive text is divided into three sections. Part one describes the mechanisms of GH secretion and action, including the physiology of GH and its regulation by sex steroids and thyroid hormones, the effects of both under nutrition and obesity on GH secretion, and the metabolic effects of human recombinant GH therapy. The second section covers diagnostic strategies and tests for GH deficiency in both children and adults, including MRI of the pituitary. The final section describes the different etiologies of GH deficiency, from molecular mechanisms and gene abnormalities to cranial radiation and traumatic brain injury, along with syndromes related to this deficiency. Presenting underlying mechanisms and pathologies, as well as diagnostic methods, Growth Hormone Deficiency will provide the most up-to-date essential information and evidence on this condition for the clinical endocrinologist.

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Produktdetails

• Verlag: Springer Nature Switzerland
• Seitenzahl: 228
• Erscheinungstermin: 4. Juli 2016
• Englisch
• ISBN-13: 9783319280387
• Artikelnr.: 46927421

Autorenporträt

Laurie E. Cohen, MD, Director of Clinical Operations, Division of Endocrinology, Director, Neuroendocrinology Program, Boston Children's Hospital, Boston, MA, USA

Inhaltsangabe

1. Introduction: Discovery of Growth Hormone and Synthesisof Recombinant Human Growth Hormone.- Part I Mechanisms of Human Growth HormoneSecretion and Action.- 2. Growth HormonePhysiology.- 3. Sex Steroids and Growth.- 4.Influence of Thyroid Hormone on Growth Hormone Secretion and Action.- 5.Undernutrition, Inflammation and Catabolic Illness and Growth Hormone Secretion.-6. Obesity and Growth Hormone Secretion.- 7. Metabolic Benefits of GrowthHormone Therapy.- Part II Diagnosis of Human Growth Hormone Deficiency.- 8. LaboratoryDiagnosis of Growth Hormone Deficiency in Children.- 9. Laboratory Diagnosis ofGrowth Hormone Deficiency in Adults.- 10. Pituitary Gland Imaging inGrowth Hormone Deficiency.- Part III Etiologies of Human Growth HormoneDeficiency.- 11. Growth Hormone Releasing Hormone Receptor and Growth HormoneGene Abnormalities.- 12. Combined Pituitary Hormone Deficiency.- 13. CranialRadiation and Growth Hormone Deficiency.- 14. Traumatic Brain Injuryand GrowthHormone Deficiency.- 15. Syndromes Associated with Growth HormoneDeficiency.