Handbook of Biomedical Nonlinear Optical Microscopy (eBook, PDF)

Redaktion: Masters, Barry R.; So, Peter

• Format: PDF

Produktbeschreibung

The Handbook of Biomedical Nonlinear Optical Microscopy provides comprehensive treatment of the theories, techniques, and biomedical applications of nonlinear optics and microscopy for cell biologists, life scientists, biomedical engineers, and clinicians. The chapters are separated into basic and advanced sections, and provide both textual and graphical illustrations of all key concepts. The more basic sections are aimed at life scientists without advanced training in physics and mathematics, and tutorials are provided for the more challenging sections. The first part of the Handbook introduces the historical context of nonlinear microscopy. The second part presents the nonlinear optical theory of two- and multiphoton excited fluorescence (TPE, MPE) spectroscopy, second and third harmonic generation (SHG, THG) spectroscopy, and coherent anti-Stokes Raman spectroscopy (CARS). The third part introduces modern microscopic and spectroscopic instrumentation and techniques that are based on nonlinear optics. The fourth part provides key applications of nonlinear microscopy to the biomedical area: neurobiology, immunology, tumor biology, developmental biology, dermatology, and cellular metabolism. There are also chapters on nonlinear molecular probes, cellular damage, and nanoprocessing.

---

Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, BG, CY, CZ, D, DK, EW, E, FIN, F, GR, HR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.

Produktdetails

• Verlag: Oxford University Press
• Erscheinungstermin: 19. Mai 2008
• Englisch
• ISBN-13: 9780198036821
• Artikelnr.: 38152011

Autorenporträt

Professor Peter T. C. So is a Professor of Mechanical Engineering and Biological Engineering at the Massachusetts Institute of Technology (MIT), Cambridge, MA. He received a B.S. degree in physics and mathematics in 1986 from the Harvey Mudd College and a Ph.D. degree in physics in 1992 from Princeton University. Professor So joined MIT as a faculty member in 1996. Professor So has published over 75 research papers in refereed journals, over 30 refereed conference proceedings, many book chapters, and numerous scientific abstracts. He is also the co-inventor of five patents related to microscopy and instrumentation. Barry R. Masters is a visiting scientist in the Department of Biological Engineering at the Massachusetts Institute of Technology and a visiting scholar in the Department of the History of Science at Harvard University. He was formerly a professor in anatomy at the Uniformed Services University of the Health Sciences. He is a Fellow of the Optical Society of America (OSA), the International Society for Optical Engineering (SPIE), and the American Association for the Advancement of Science (AAAS). Professor Masters has published 81 refereed research papers and 128 book chapters and articles. He is the editor or author of Noninvasive Diagnostic Techniques in Ophthalmology; Medical Optical Tomography: Functional Imaging and Monitoring; Selected Papers on Confocal Microscopy; Selected Papers on Optical Low-Coherence Reflectometry and Tomography; Selected Papers on Multiphoton Excitation Microscopy; Confocal Microscopy and Multiphoton Excitation Microscopy: the Genesis of Live Cell Imaging; and with Peter So, Handbook of Biomedical Nonlinear Optical Microscopy. Professor Masters is a member of the editorial board of Graefe's Archive for Clinical and Experimental Ophthalmology. His research interests include the development of in vivo microscopy of the human eye and skin, biomedical imaging and spectroscopy, and the fractal analysis of branching vascular patterns.

Inhaltsangabe

* Part I. Historical Development of Nonlinear Optical Spectroscopy and
Microscopy
* Introduction to Part I: Historical Development of Nonlinear Optical
Microscopy and Spectroscopy
* Chapter 1: The Genesis of Nonlinear Optical Microscopies and their
Impact on Modern Developments.
* Chapter 2: The Scientific Life of Maria Göppert-Mayer
* Chapter 3: The History of Perturbation Theory from Astronomy to
Quantum Mechanics
* Chapter 4: English Translations of and Translator's Notes on Maria
Göppert-Mayer's Theory of Two-Quantum Processes
* Part II. Nonlinear Optical Spectroscopy
* Introduction to Part II: Nonlinear Optical Spectroscopy
* Chapter 5: Classical and Quantum Theory of One-Photon and Multiphoton
Fluorescence Spectroscopy
* Chapter 6: Second- and Higher-Order Harmonic Generation
* Chapter 7: Theory of Spontaneous and Coherent Raman Scattering
* Part III. Nonlinear Optical Instruments for Microscopic Imaging and
Analysis
* Introduction to Part III: Nonlinear Optical Instruments for
Microscopic Imaging and Analysis: Review and Forecast
* Chapter 8: Laser Sources for Non-Linear Microscopy
* Chapter 9: Ultrashort Optical Pulse Delivery for Nonlinear Optical
Microscopy
* Chapter 10: An Optical Design Primer for Nonlinear Optical Microscopy
* Chapter 11: Image Formation in Multiphoton Fluorescence Microscopy
* Chapter 12: Signal Detection and Processing in Nonlinear Optical
Microscopes
* Chapter 13: Multiphoton Excitation of Fluorescent Probes
* Chapter 14: Multiphoton-Induced Cell Damage
* Chapter 15: Applications of Second-Harmonic Generation Microscopy
* Chapter 16: Second-Harmonic Generation Imaging Microscopy of
Structural Protein
* Chapter 17: Coherent Anti-Stokes Raman Scattering (CARS) Microscopy:
Instrumentation and Applications
* Chapter 18: High-speed Imaging Using Multiphoton Excitation
* Chapter 19: Nonlinear Multi-Spectral Optical Imaging Microscopy:
Concepts, Instrumentation, and Applications
* Chapter 20: Multiphoton Polarization Microscopy
* Chapter 21: Lifetime-Resolved Imaging in Nonlinear Microscopy
* Chapter 22: Förster Resonance Energy Transfer (FRET)
* Chapter 23: Two-Photon Förster Resonance Energy Transfer (FRET)
Microscopy
* Chapter 24: Diffraction Unlimited Far-Field Fluorescence Microscopy
* Chapter 25: Two-Photon Fluorescence Correlation Spectroscopy
* Chapter 26: Photobleaching and Recovery with Nonlinear Microscopy
* Chapter 27: Femtosecond Laser Nanoprocessing
* Part IV. Biomedical Applications of Nonlinear Optical Microscopy
* Introduction to Part IV: Biomedical Applications of Nonlinear Optical
Microscopy
* Chapter 28: Pioneering Applications Of Two-Photon Microscopy To
Mammalian Neurophysiology: Seven Case Studies
* Chapter 29: Applications of Non-Linear Intravital Microscopy in Tumor
Biology
* Chapter 30: Immunology Based on Nonlinear Optical Microscopy
* Chapter 31: Multiphoton Imaging in Animal Development
* Chapter 32: Nonlinear Microscopy Applied to Dermatology
* Chapter 33: Cellular Metabolism Monitored by NAD(P)H Imaging with
Two-Photon Excitation Microscopy