The text begins by outlining historical theories of disease causation, prevention and cure, to provide a contextual understanding for the reader. The ensuing chapters describe how historical diseases acquired their traditional monikers (Spanish flu, ship fever, ague, blue death, breakbone fever, scarlet fever, etc.) and how they were treated before the era of modern medicine. Emphasis is placed on the impact of disease outbreaks on society and how the understanding, treatment, and prevention of these diseases developed over time. The threat of historical disease reemergence due to waning vaccine immunities, vaccine hesitancy, antibiotic resistance and climate change is noted as a subtext throughout the book - a peril of global concern at this time.
The book covers a large array of historical diseases, grouped for clarity and understanding within the broad categories of contagious diseases, vector-borne/zoonotic diseases, fecal-oral diseases, sexually transmitted diseases, substance use disorders, parasitic diseases, nutritional diseases, fungal diseases, and soil-related bacterial diseases.
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