Phyllis R. Brown

HPLC in Nucleic Acid Research (eBook, ePUB)

Methods and Applications

• Format: ePub

Produktbeschreibung

This book gives the pertinent information on the high pressure liquid chromatography (HPLC) analyses of all the compounds of interest in nucleic acid metabolism. It aids chromatographers, biochemists, biomedical researchers, and chemists by giving information on applications of HPLC technique.

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Produktdetails

• Verlag: Taylor & Francis eBooks
• Seitenzahl: 424
• Erscheinungstermin: 18. August 2020
• Englisch
• ISBN-13: 9781000146547
• Artikelnr.: 68423751

Autorenporträt

Phyllis R. Brown, PhD, Professor Emerita of Chemistry at the University of Rhode Island is credited with over two hundred articles in scientific journals and known as "the Mother of High Pressure Liquid Chromatography." She wrote five books, served as editor of many publications, was a gifted teacher and advisor to her graduate students. In retirement she dedicated herself to her husband, her many circles of friends in science and the community, and her children and their families.

Inhaltsangabe

Part I: Overview 1. Nucleic Acid Research 2. Structures, Properties, and
Chromatographic Behavior of Nucleic Acid Constituents Part II: Methodology
3. Sample Preparation 4. Chromatography 5. Peak Identification 6.
Quantitative Analysis in Liquid Chromatography 7. Microbore Columns 8.
Detection Systems 9. Mobile Phase Control Part III: Applications 10.
Nucleic Acids 11. Oligonucleotides 12. Free Nucleotides in Biological
Samples 13. Free Nucleosides and Their Bases in Physiological Fluids 14.
Cyclic Nucleotides 15. Enzyme Assays by HPLC 16. Nucleotide Coenzymes 17.
HPLC Analysis of Pyrimidine and Purine Anti-metabolite Drugs 18. Central
Nervous System Drugs (Methylxanthine Drugs) 19. Nucleic Acid Constituents
in Disease Processes