Hypertension and Hormone Mechanisms (eBook, PDF)

Redaktion: Carey, Robert M.

• Format: PDF

Produktbeschreibung

Hypertension, a major risk factor for cardiovascular disease and stroke, is present in approximately one-quarter of the adult population of Western societies. Advances in the study and treatment of this condition are captured in this exceptionally important book. In Hypertension and Hormonal Mechanisms, distinguished panels of leading experts discuss new developments in hormones/autacoids related to hypertension. During the past decade, truly remarkable advances have been made in the identification of new components of the renin-angiotensin system. This book also provides the most up to date advancements in topics such as the importance of diabetes and obesity in hypertension and the new role of calcitonsin gene-related peptide (CGRP) in hypertension. Hypertension and Hormonal Mechanisms, written by the world's experts in this field, aims to open new doors leading researchers closer to understanding the etiology and pathogenesis of primary (essential) hypertension, and to stimulate active research in the fundamental mechanisms of hypertension so that new therapies, and even prevention, can be realized in the not-too-distant future.

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Produktdetails

• Verlag: Humana Press
• Seitenzahl: 378
• Erscheinungstermin: 21. Juni 2010
• Englisch
• ISBN-13: 9781592599875
• Artikelnr.: 43982888

Inhaltsangabe

New Developments in the Renin-Angiotensin System.- The Intrarenal Renin-Angiotensin System.- Cardiac and Vascular Renin-Angiotensin Systems.- Regulation of Cardiovascular Control Mechanisms by Angiotensin-(1-7) and Angiotensin-Converting Enzyme 2.- Angiotensin IV Binding Site.- Angiotensin AT2 Receptors in Blood Pressure Regulation.- Angiotensin II and Inflammation.- Aldosterone and Vascular Damage.- The Sympatho-Adrenal System in Hypertension II.- Neurogenic Human Hypertension.- Calcitonin Gene-Related Peptide and Hypertension.- The Renal Dopaminergic System, Hypertension, and Salt Sensitivity.- Metabolic Disorders and Hypertension.- Insulin Resistance and Hypertension.- Fatty Acids, Cell Signaling, and Cardiovascular Risk.- Goal-Oriented Hypertension Management in Diabetic and Nondiabetic Patients.- Endothelial Hormones and Autocoids in Hypertension.- Nitric Oxide and Hypertension.- Role of Endothelin-1 in Hypertension.- The Kallikrein-Kinin System and Hypertension.- Other Hormonal Systems and Hypertension.- Physiology of Natriuretic Peptides and Their Receptors.- Sex Steroids and Hypertension.- The Lipoxygenase System in the Vasculature and Hypertension.

Rezensionen

From the reviews:

"This is a comprehensive overview of pathophysiology of hypertension. ... The book is targeted at both scientists and clinicians with the goal of providing a basic foundation to better understand mechanisms involved in hypertension as well as stimulate active research to better understand the fundamental mechanisms of the disease. ... useful and very thorough summary of the hormonal mechanisms of hypertension. It is an excellent resource for clinicians and scientists involved in the treatment of hypertension as well as those engaging in basic science research." (Irena Duka, Doody's Review Service, December, 2007)

"The book provides a unique review of the latest developments and discoveries in the endocrinology of hypertension . ... it also provides the reader with the most recent discoveries brought about by basic clinical science research. ... This book will be of utmost interest to clinicians and basic scientists ... as well as to specialists such as endocrinologists, cardiologists, and nephrologists. I strongly recommend that it should be available in all medical school libraries." (Edgar V. Lerma, JAMA, May, 2008)

"As edited by Dr. Carey, a well-recognized investigator in this field, leading experts provide very comprehensive discussions of the effect of the different hormonal systems on progression of cardiovascular disease. ... this book provides a nice combination of both basic science and clinical considerations of hormonal causes of hypertension and vascular disease. ... Overall, the book will serve as a valuable resource for scientists and clinicians interested in the underlying mechanisms of hypertension and vascular disease." (David A. Calhoun, Endocrinology, Vol. 33 (4), April, 2008)