IgG4-Related Kidney Disease (eBook, PDF)

Redaktion: Saito, Takao; Kawano, Mitsuhiro; Saeki, Takako; Nakashima, Hitoshi; Stone, John H.

• Format: PDF

Produktbeschreibung

This book offers a detailed review of the pathological and imaging features, diagnosis and treatment of IgG4-Related Kidney Disease (IgG4-RKD). IgG4-related disease (IgG4-RD), which is characterized by an elevated serum IgG4 level and infiltration of systemic organs by IgG4 positive plasma cells, is a newly recognized systemic disease. Diverse renal manifestations including specific tubulointerstitial nephritis, membranous nephropathy, and tumor-like urological diseases extending to the pelvis and urinary tract in IgG4-RD have been reported and are recently attracting attention as IgG4-RKD. In this book, leading researchers in the field present the latest insights into the broad spectrum of IgG4-RKD characteristics. In addition, they provide a detailed explanation of the pathology of IgG4-RKD including comparisons between the kidney and other affected organs, such as the lacrimal, salivary glands and pancreas in the histopathological section. IgG4-Related Kidney Disease will have a major impact on future immunological and nephrological studies and offers a useful resource not only for nephrologists but also general physicians and investigators in related fields.

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Produktdetails

• Verlag: Springer Japan
• Seitenzahl: 311
• Erscheinungstermin: 9. November 2016
• Englisch
• ISBN-13: 9784431556879
• Artikelnr.: 53152109

Autorenporträt

Takao Saito, Emeritus Professor, Faculty of Medicine, Fukuoka University John H. Stone, Massachusetts General Hospital  Hitoshi Nakashima, Division of Nephrology & Rheumatology, Department of Internal Medicine, Fukuoka University  Takako Saeki, Department of Internal Medicine, Nagaoka Red Cross Hospital  Mitsuhiro Kawano, Division of Rheumatology, Department of Internal Medicine, Kanazawa University

Inhaltsangabe

Part I. General Remarks.-1. IgG4-Related Disease: History and Overview.-2. IgG4-Related Disease: Pathological Features and Differential Diagnosis.-3. Potential Pathways in The Pathogenesis of IgG4-Related Disease.- 4. Does IgG4-Related Disease Have an Autoimmune Basis?.-5. Plasmablasts: A Promising Biomarker in IgG4-RD.-Part II. Features of IgG4-Related Ridney Disease and Associated Conditions.-6. Overview of IgG4-Related Kidney Disease.-7. IgG4-Related Kidney Disease: Clinical and Laboratory Features.-8. Imaging Findings.- 9. Characteristic Tubulointerstitial Nephritis in IgG4-Related Kidney Disease.-10. Electron Microscopic Findings.-11. IgG4-RelatedKidney Disease: Pathological Features -Membranous Glomerulonephritis.-12. IgG4-RelatedKidney Disease: Pathological Features -Other Glomerular Disease.-13. IgG4-Related kKidneyDiseases and Conditions: Renal Pelvic and Ureteral Diseases.-14. Retroperitoneal Fibrosis/Periaortitis and Hydronephrosis.-15. Other Urogenital Lesions (Testis, Paratesticular Lesion, Bladder, Prostate etc.).-16. Characteristic Distribution of Inflammatory Lesions in IgG4-Related Kidney Disease: Findings from Autopsy Case Series.-17. Diagnosis of IgG4-Related Kidney Disease.-18. Pathogenesis of IgG4-Related Kidney Disease.-Part III. Treatment of IgG4-RD and IgG4-RKD.-19. Corticosteroid Therapy for IgG4-Related Kidney Disease.-20. Targeting the B Cell Lineage in IgG4-Related Disease.-Part IV. Differential Diagnosis of IgG4-RKD.-21. Differential Diagnosis of IgG4-Related Tubulointerstitial Nephritis -An Overview.-22. Differential Diagnosis (1): ANCA Associated Vasculitis.-23. Differential Diagnosis (2): Castleman Disease.-24. Differential Diagnosis (3): Sjögren Syndrome.-25. Differential Diagnosis: Lupus Nephritis and IgG4-Related Kidney Disease.-Part V. Lessons from Cases.-26. Multicentric Castleman's Disease Mimicking IgG4-Related Disease; A Case Report.-27. A Case of Concurrent IgG4-Related Kidney Disease and Lupus Nephritis.