Immunobiology of Bacterial CpG-DNA (eBook, PDF)

Redaktion: Wagner, H.

• Format: PDF

Produktbeschreibung

Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules and pro-inflammatory cytokines. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses. This book is the first comprehensive review of the data emerging in this field.

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Produktdetails

• Verlag: Springer Berlin Heidelberg
• Seitenzahl: 246
• Erscheinungstermin: 6. Dezember 2012
• Englisch
• ISBN-13: 9783642596728
• Artikelnr.: 53091658