Immunotherapy and Biomarkers in Neurodegenerative Disorders (eBook, PDF)

Redaktion: Ingelsson, Martin; Lannfelt, Lars

• Format: PDF

Produktbeschreibung

This practical volume examines a number of topics that explore the current status of immunotherapy and diagnostic markers for neurodegenerative disorders. With a focus on Alzheimer's disease, the first sections of the book examine immunotherapeutic approaches for the aforementioned disease as well as for Parkinson's disease and Huntington's disease, amongst others. The last section of the book covers the importance of biomarker techniques to catch these diseases early enough for the treatments to be most useful. Written for the Methods in Pharmacology and Toxicology series, this book contains the kind of detailed descriptions and implementation advice that will offer a smooth transition into the lab.

Authoritative and useful, Immunotherapy and Biomarkers in Neurodegenerative Disorders aims to aid in the continued progress in the development of novel immune-based drugs and diagnostic tools for these devastating brain diseases.

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Produktdetails

• Verlag: Springer New York
• Seitenzahl: 289
• Erscheinungstermin: 13. April 2016
• Englisch
• ISBN-13: 9781493935604
• Artikelnr.: 64700476

Inhaltsangabe

Immunotherapy Against Amyloid-beta in Alzheimer's Disease: AnOverview.- Active Immunization Against the Amyloid-beta Peptide.- ImmunotherapyAgainst N-Truncated Amyloid-beta Oligomers.- Immunotherapy Against Amyloid-betaProtofibrils: Opportunities and Challenges.- Immunotherapy Against -SynucleinPathology.- Extracellular -Synuclein as a Target for Immunotherapy.- Immunotherapyof Parkinson's Disease.- TauImmunotherapy.- Active and Passive Immunotherapy Against Tau: Effectsand Potential Mechanisms.- Immunotherapy on Experimental Models forHuntington's Disease.- Cerebrospinal Fluid Biomarkers in Alzheimer's Disease.- VolumetricMRI as a Diagnostic Tool in Alzheimer's Disease.- PET Imaging as a DiagnosticTool in Alzheimer´s Disease.- lpha-Synuclein as a Diagnostic Biomarker forParkinson's Disease.- Imaging as a Diagnostic Tool in Parkinson's Disease.- MassSpectrometry-Based Proteomics in Biomarker Discovery for NeurodegenerativeDiseases.