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Inflammatory Bowel Diseases: A Clinician's Guide provides practical guidance for the diagnosis and management of those suspected or known to have one of the forms of these complex diseases. It is perfect both for gastroenterology trainees learning to care for these patients and the experienced physician as a concise and practical resource for day to day use. Written by the experts, Inflammatory Bowel Diseases: A Clinician's Guide is an essential tool for all gastroenterologists managing patients with inflammatory bowel disease.
Inflammatory Bowel Diseases: A Clinician's Guide provides practical guidance for the diagnosis and management of those suspected or known to have one of the forms of these complex diseases. It is perfect both for gastroenterology trainees learning to care for these patients and the experienced physician as a concise and practical resource for day to day use. Written by the experts, Inflammatory Bowel Diseases: A Clinician's Guide is an essential tool for all gastroenterologists managing patients with inflammatory bowel disease.
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Ashwin N. Ananthakrishnan MD, MPH, Assistant Professor of Medicine, Harvard Medical School; Director, Crohn's and Colitis Center, Massachusetts General Hospital, Boston, MA, USA. Ramnik J. Xavier MD, Kurt Isselbacher Professor of Medicine, Harvard Medical School; Chief of Gastroenterology, Massachusetts General Hospital; Institute Member, Broad Institute of MIT and Harvard, Boston, MA, USA. Daniel K. Podolsky MD, President, University of Texas Southwestern Medical Center; Professor of Internal Medicine, University of Texas Southwestern Medical School, Dallas, TX, USA.
Inhaltsangabe
Preface
Section I Pathogenesis and Clinical Features
1 Epidemiology and Pathogenesis
Clinical Take Home Messages
Epidemiology
Pathogenesis
Genetics
Microbiome
Environmental Triggers
Case Studies and Multiple Choice Questions
References
Answers to Questions
2 Clinical Features and Diagnosis of Crohn's Disease
Clinical Take Home Messages
Clinical Features
Disease Course and Natural History
Diagnosis
History and Physical Examination
Laboratory Investigations
Serologic Markers
Endoscopy
Histology
Imaging Studies
Case Studies and Multiple Choice Questions
References
Answers to Questions
3 Clinical Features and Diagnosis of Ulcerative Colitis
Clinical Take Home Messages
Clinical Features
Disease Course and Natural History
Diagnosis
History and Physical Examination
Laboratory Investigations
Serologic Markers
Endoscopy
Histology
Imaging Studies
Differential Diagnosis (UC and CD)
Case Studies and Multiple Choice Questions
References
Answers to Questions
4 Extraintestinal Manifestations of Inflammatory Bowel Diseases
Clinical Take Home Messages
Arthritis and Arthropathy
Metabolic Bone Disease
Cutaneous Manifestations
Hepatobiliary Manifestations
Ophthalmologic Manifestations
Renal Complications
Thromboembolic and Cardiovascular Complications
Case Studies and Multiple Choice Questions
References
Answers to Questions
Section II Therapeutic Agents
5 Aminosalicylates
Clinical Take Home Messages
Efficacy in Ulcerative Colitis
Efficacy in Crohn's Disease
Safety
Multiple Choice Questions
References
Answers to Questions
6 Corticosteroids
Clinical Take Home Messages
Efficacy in Ulcerative Colitis
Efficacy in Crohn's Disease
Safety
Case Studies and Multiple Choice Questions
References
Answers to Questions
7 Immunomodulators
Clinical Take Home Messages
Thiopurines
Efficacy in Ulcerative Colitis
Efficacy in Crohn's Disease
Safety
Methotrexate
Efficacy in Ulcerative Colitis
Efficacy in Crohn's Disease
Safety
Calcineurin Inhibitors
Efficacy in Ulcerative Colitis
Efficacy in Crohn's Disease
Case Studies and Multiple Choice Questions
References
Answers to Questions
8 Biologic Therapies
Clinical Take Home Messages
Infliximab
Efficacy in Ulcerative Colitis
Efficacy in Crohn's Disease
Safety
Adalimumab
Efficacy in Ulcerative Colitis
Efficacy in Crohn's Disease
Certolizumab Pegol
Efficacy in Crohn's Disease
Golimumab
Natalizumab
Vedolizumab
Newer Therapies
Case Studies and Multiple Choice Questions
References
Answers to Questions
9 Antibiotics
Clinical Take Home Messages
Efficacy in Ulcerative Colitis
Efficacy in Crohn's Disease
Other Microbial Modification Methods - Probiotics a
