An authoritative review of the interindividual variability in drug metabolism in humans, this book highlights the general background and addresses variability of drug metabolism in vivo. With the help of an international panel of contributors, the editors explore the interindividual variability of the main drug metabolizing enzymes: CYP-450s, glucuronosyl transferase, sulfotransferases and glutathione transferases in human liver and extrahepatic tissues. This book is essential reading for researchers from both academia and the pharmaceutical industry as well as advanced undergraduates and postgraduates in pharmacology, clinical pharmacology, toxicology, biochemistry and epidemiology.
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