Andrew F. Wilks, Ailsa G. Harpur

Intracellular Signal Transduction: The JAK-STAT Pathway (eBook, PDF)

• Format: PDF

Produktbeschreibung

This book is the first one written about the JAK/STAT pathway. The JAK (Janus Kinase) Protein tyrosine kinases are novel phosphotransferases absolutely required for cellular signalling downstream of non-catalytic cytokine receptors (amongst others). These molecules are components in pathways utilising the STAT (Signal Transducers and Activators of Transcription) transcription factors. The basic components of the JAK/STAT pathway are covered in detail, and the centre piece of the book is a guided tour of the pathway itself. An interesting addition to the book is the chapter on the use of Drosophila melanogaster as a genetic system to probe the pathway at the whole organism level. The book is targeted to researchers who have an interest in intracellular signalling.

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Produktdetails

• Verlag: Springer Berlin Heidelberg
• Seitenzahl: 209
• Erscheinungstermin: 29. Juni 2013
• Englisch
• ISBN-13: 9783662220504
• Artikelnr.: 53102426