Naruya Saitou

Introduction to Evolutionary Genomics (eBook, PDF)

• Format: PDF

Produktbeschreibung

Evolutionary genomics is a new discipline that bridges the fields of molecular evolution, bioinformatics and genomics in order to provide a unique perspective on the history of life.

This easy-to-follow textbook is the first of its kind to explain the fundamentals of evolutionary genomics. The comprehensive coverage includes concise descriptions of a variety of genome organizations, a thorough discussion of the methods used, and a detailed review of genome sequence processing procedures. The opening chapters also provide the necessary basics for readers unfamiliar with evolutionary studies.

Topics and features:

• Introduces the basics of molecular biology, DNA replication, mutation, phylogeny, neutral evolution, and natural selection
• Presents a brief evolutionary history of life from the primordial seas to the emergence of modern humans
• Describes the genomes of prokaryotes, eukaryotes, vertebrates, and humans
• Reviews methods forgenome sequencing, phenotype data collection, homology searches and analysis, and phylogenetic tree and network building
• Discusses databases of genome sequences and related information, evolutionary distances, and population genomics
• Provides supplementary material at the website http://www.saitou-naruya-laboratory.org/Evolutionary_Genomics/

This essential text/reference provides an easy-to-read introduction to the field for undergraduate and graduate students, post-doctoral fellows, and established researchers from both computer science and the biological sciences.

Dr. Naruya Saitou is a Professor in the Division of Population Genetics at the National Institute of Genetics, and a Professor in the Department of Genetics at the Graduate University for Advanced Studies, Mishima, Japan. He is also a Professor in the Department of Biological Sciences at the University of Tokyo, Japan.

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Produktdetails

• Verlag: Springer London
• Seitenzahl: 461
• Erscheinungstermin: 22. Januar 2014
• Englisch
• ISBN-13: 9781447153047
• Artikelnr.: 43786466

Autorenporträt

Dr. Naruya Saitou is a Professor in the Division of Population Genetics at the National Institute of Genetics, and a Professor in the Department of Genetics at the Graduate University for Advanced Studies, Mishima, Japan. He is also a Professor in the Department of Biological Sciences at the University of Tokyo, Japan.

Inhaltsangabe

Part I: Basic Processes of Genome Evolution.- Replication, Transcription, and Translation.- Proteins.- Mutation.- Phylogeny.- Neutral Evolution.- Natural Selection.- Part II: Evolving Genomes.- A Brief History of Life.- Prokaryote Genomes.- Eukaryote Genomes.- Virus Genomes.- Vertebrate Genomes.- The Human Genome.- Part III: Methods for Evolutionary Genomics.- Genome and Transcriptome Sequencing.- Omic Worlds and their Databases.- Homology Search and Multiple Alignment.- Evolutionary Distances.- Phylogeny Construction.- Human Population Genomics.