Barna Szabó, Ivo Babuska

Introduction to Finite Element Analysis (eBook, ePUB)

Formulation, Verification and Validation

• Format: ePub

Produktbeschreibung

When using numerical simulation to make a decision, how can its reliability be determined? What are the common pitfalls and mistakes when assessing the trustworthiness of computed information, and how can they be avoided? Whenever numerical simulation is employed in connection with engineering decision-making, there is an implied expectation of reliability: one cannot base decisions on computed information without believing that information is reliable enough to support those decisions. Using mathematical models to show the reliability of computer-generated information is an essential part of any modelling effort. Giving users of finite element analysis (FEA) software an introduction to verification and validation procedures, this book thoroughly covers the fundamentals of assuring reliability in numerical simulation. The renowned authors systematically guide readers through the basic theory and algorithmic structure of the finite element method, using helpful examples and exercises throughout. * Delivers the tools needed to have a working knowledge of the finite element method * Illustrates the concepts and procedures of verification and validation * Explains the process of conceptualization supported by virtual experimentation * Describes the convergence characteristics of the h-, p- and hp-methods * Covers the hierarchic view of mathematical models and finite element spaces * Uses examples and exercises which illustrate the techniques and procedures of quality assurance * Ideal for mechanical and structural engineering students, practicing engineers and applied mathematicians * Includes parameter-controlled examples of solved problems in a companion website (href="http://www.wiley.com/go/szabo">www.wiley.com/go/szabo)

---

Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, BG, CY, CZ, D, DK, EW, E, FIN, F, GR, HR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.

Produktdetails

• Verlag: For Dummies
• Seitenzahl: 372
• Erscheinungstermin: 22. März 2011
• Englisch
• ISBN-13: 9781119993483
• Artikelnr.: 38258089

Autorenporträt

Barna Szabó is co-founder and president of Engineering Software Research and Development, Inc. (ESRD), the company that produces the professional finite element analysis software StressCheck®. Prior to his retirement from the School of Engineering and Applied Science of Washington University in 2006 he served as the Albert P. and Blanche Y. Greensfelder Professor of Mechanics. His primary research interest is assurance of quality and reliability in the numerical stimulation of structural and mechanical systems by the finite element method. He has published over 150 papers in refereed technical journals. Several of them in collaboration with Professor Ivo BabuSka, with whom he also published a book on finite element analysis (John Wiley & Sons, Inc., 1991). He is a founding member and Fellow of the US Association for Computational Mechanics. Among his honors are election to the Hungarian Academy of Sciences as External Member and an honorary doctorate. Ivo BabuSka's research has been concerned mainly with the reliability of computational analysis of mathematical problems and their applications, especially by the finite element method. He was the first to address a posteriori error estimation and adaptivity in finite element analysis. His research papers on these subjects published in the 1970s have been widely cited. His joint work with Barna Szabó on the p-version of the finite element method established the theoretical foundations and the algorithmic structure for this method. His recent work has been concerned with the mathematical formulation and treatment of uncertainties which are present in every mathematical model. In recognition of his numerous important contributions, Professor BabuSka received may honors, which include honorary doctorates, medals and prizes and election to prestigious academies.

Inhaltsangabe

List of Contributors xiii
Preface xv
1 Biosynthesis and Metabolism of Starch and Sugars 1
Frederik Börnke and Sophia Sonnewald
1.1 Introduction 1
1.2 Carbon Partitioning in Mesophyll Cells 2
1.3 Sucrose Biosynthesis in Source Leaves 3
1.4 Starch Metabolism in Source Leaves 7
1.5 Sucrose to Starch Conversion in Storage Organs 12
1.6 Metabolic Engineering of Carbohydrate Metabolism 14
1.7 Engineering Soluble Sugars 16
1.8 Production of Novel Carbohydrates in Transgenic Plants 17
1.9 Network Analysis of Carbohydrate Metabolism 18
Acknowledgements 19
References 19
2 Lipid Biosynthesis 27
David Hildebrand
2.1 Introduction 27
2.2 Fatty Acid Synthesis 29
2.3 Fatty Acid Desaturases 32
2.4 Lipid Signals 38
2.5 Algae 38
2.6 Membrane Synthesis 39
2.7 TAG Biosynthesis 43
2.8 Genetic Engineering of Oilseed for Industrial Uses 46
2.9 Plant Oils as a Renewable Resource 48
Acknowledgements 51
References 52
3 Symbiotic Nitrogen Fixation 67
Hiroshi Kouchi
3.1 Nitrogen Fixing Organisms and the Nitrogenase System 67
3.2 Symbiotic Nodule Formation in Legume Plants 70
3.3 Mutual Interactions between Host Cells and Bacteroids in Legume Nodules
76
3.4 Molecular Genetic Approaches to the Host Regulation of Nitrogen
Fixation 83
Acknowledgements 92
References 92
4 Sulfur Metabolism 103
Hideki Takahashi
4.1 Introduction 103
4.2 Sulfate Transport 104
4.3 Sulfate Reduction 111
4.4 Cysteine Biosynthesis 114
4.5 Methionine Biosynthesis 117
4.6 Regulators for Coordination of Sulfur Metabolism 118
References 121
5 Nucleotide Metabolism 135
Rita Zrenner and Hiroshi Ashihara
5.1 Introduction 135
5.2 Pyrimidine Metabolism 136
5.3 Purine Metabolism 142
5.4 Pyridine Metabolism 149
5.5 Biotechnological Approaches 152
References 156
6 Purine Alkaloid Metabolism 163
Hiroshi Ashihara, Shinjiro Ogita and Alan Crozier
6.1 Introduction 163
6.2 Classification of Purine Alkaloids 166
6.3 Occurrence of Purine Alkaloids 166
6.4 Biosynthesis of Caffeine 167
6.5 Catabolism of Caffeine 171
6.6 Physiological and Ecological Aspects of Purine Alkaloid Metabolism in
Plants 173
6.7 Metabolic Engineering of Caffeine In Planta 176
References 184
7 Nicotine Biosynthesis 191
Tsubasa Shoji and Takashi Hashimoto
7.1 Introduction 191
7.2 Pathways and Enzymes 192
7.3 Compartmentation and Trafficking 200
7.4 Gene Regulation 203
7.5 Metabolic Engineering 207
7.6 Recent Developments 208
7.7 Summary 208
References 208
8 Terpenoid Biosynthesis 217
Dae-Kyun Ro
8.1 Introduction 217
8.2 Terpenoid Diversity 218
8.3 Mechanistic Aspects of Terpenoid Biogenesis 222
8.4 Terpene Synthase - Structure, Evolution and Engineering 223
8.5 Two Distinct Pathways for Isopentenyl Diphosphate (IPP) Biosynthesis
225
8.6 Subcellular and Cellular Compartmentalisations of Terpenoid Metabolism
228
8.7 Gene Clusters in Terpenoid Metabolism 230
8.8 Metabolic Engineering of Terpenoid Metabolism 231
8.9 Concluding Remarks 235
References 235
9 Benzylisoquinoline Alkaloid Biosynthesis 241
Isabel Desgagn¿e-Penix and Peter J Facchini
9.1 Introduction 241
9.2 Biosynthesis 242
9.3 Localisation and Transport of Benzylisoquinoline Alkaloids and their
Biosynthetic Enzymes 249
9.3.1 Cellular and Subcellular Localisation 249
9.3.2 Transport 251
9.4 Regulation 251
9.4.1 Gene Regulation 251
9.4.2 Signal Transduction 251
9.5 Application to Biotechnology 252
9.5.1 Mutagenesis 252
9.5.2 Genetic Transformation and Metabolic Engineering 252
9.5.3 Metabolic Engineering 254
9.6 Conclusions 254
References 254
10 Monoterpenoid Indole Alkaloid Biosynthesis 263
Vincenzo De Luca
10.1 Introduction 263
10.2 Monoterpenoid Indole Alkaloid (MIA) Biosynthesis 265
10.3 MIA Pathway Gene Discovery will be Enhanced by Large-Scale Sequencing
and Comparative Analyses 271
10.4 Developmental and Environmental Regulation of MIA Biosynthesis 272
10.5 Metabolic Engineering using Enzymes with Altered Substrate Specificity
282
10.6 Conclusion 282
Acknowledgements 283
References 283
11 Flavonoid Biosynthesis 293
Indu B. Jaganath and Alan Crozier
11.1 Introduction 293
11.2 Advances in Molecular Approaches for Flavonoid Biosynthetic Pathway
Elucidation 294
11.3 The Flavonoid Biosynthetic Pathway as it is Today 299
11.4 Conclusions 311
References 313
12 Pigment Biosynthesis I. Anthocyanins 321
Yoshihiro Ozeki, Yuki Matsuba, Yutaka Abe, Naoyuki Umemoto and Nobuhiro
Sasaki
12.1 Introduction 321
12.2 The Anthocyanin Biosynthetic Pathway 322
12.3 Glycosylation of Anthocyanidins 325
12.4 Acylation of Anthocyanin Glycosides 327
12.5 Transport of Anthocyanins from Cytosol to Vacuoles 331
12.6 Concluding Remarks 335
References 336
13 Pigment Biosynthesis II: Betacyanins and Carotenoids 343
Masaaki Sakuta and Akemi Ohmiya
13.1 Betacyanins 343
13.2 Carotenoids 350
13.3 Metabolic Engineering of Carotenoids 357
References 361
14 Metabolomics in Plant Biotechnology 373
Yozo Okazaki, Akira Oikawa, Miyako Kusano, Fumio Matsuda and Kazuki Saito
14.1 Introduction 373
14.2 Analytical Technologies 373
14.3 Informatics Techniques 376
14.4 Biotechnological Application 378
Acknowledgements 381
References 381
Index 389 

Rezensionen

"Summing Up: Recommended. Upper-division undergraduates through professionals." (Choice, 1 January 2012)