Irreversible Electroporation (eBook, PDF)

Redaktion: Rubinsky, Boris

• Format: PDF

Produktbeschreibung

This is an brief introduction to the emerging field of irreversible electroporation in medicine. Certain electrical fields when applied across a cell can have as a sole effect the permeabilization of the cell membrane, presumable through the formation of nanoscale defects in the cell membrane. Sometimes this process leads to cell death, primarily when the electrical fields cause permanent permeabilization of the membrane and the consequent loss of cell homeostasis, in a process known as irreversible electroporation. This is an unusual mode of cell death that is not fully understood yet. While the phenomenon of irreversible electroporation may have been known for centuries it has become only recently rigorously considered in medicine for various applications of tissue ablation. A brief historical perspective of irreversible electroporation is presentedfollowed by general reviews on the theory and experiment fundamentals and by reports on the most recent theoretical, experimental and clinical studies.

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Produktdetails

• Verlag: Springer Berlin Heidelberg
• Seitenzahl: 313
• Erscheinungstermin: 25. November 2009
• Englisch
• ISBN-13: 9783642054204
• Artikelnr.: 37368118

Inhaltsangabe

History of IRE.- Basic Bioelectronics.- Review of Experimental Studies on IRE of Cells.- Review of Mathematical Models of IRE of Cells.- Mathematical Models of Heat Transfer during non Thermal IRE of Tissue.- Review of experimental Studies of IRE in Tissue.- Mathematical Models of Anisotropic.- Treatment Planning.- Electrochemotherapy and IRE.- Clinical Results with IRE (prostate).- Clinical Results with IRE (Liver, Kidney, Lung).- IRE Tissue Electroporation Systems.- Food.