Ketamine (eBook, ePUB)

Use and Abuse
Redaktion: Yew, David T.

• Format: ePub

Produktbeschreibung

This book reviews the acute and chronic effects of ketamine on both adult and developing animals and humans. Topics include pharmacological properties, impact on various organ systems, developmental neurotoxicity in the developing brain, postmortem toxicology, as well as the epidemiology of misuse and patterns of acute and chronic toxicity and the psychosocial aspects of ketamine addiction. The book also explores clinical applications at acceptable doses, including possible contribution to the treatment of depression. The broad-based coverage is designed to promote heightened attention on the subject and encourage further research into the beneficial clinical uses of ketamine.

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Produktdetails

• Verlag: Taylor & Francis
• Erscheinungstermin: 16. März 2015
• Englisch
• ISBN-13: 9781040059951
• Artikelnr.: 72279322

Autorenporträt

Professor David T. Yew is the professor emeritus of anatomy in the School of Biomedical Sciences, Chinese University of Hong Kong. He has engaged in research of human and animal neuroscience, drug discovery, and drug toxicology, using various techniques of pathology, immunocytochemistry, cytochemistry, and imaging. Professor Yew's area of specialty is research on neurodegeneration, particularly damage to the nervous system brought about by ketamine abuse, and is now one of the major global leaders in this area.

Inhaltsangabe

Ketamine use and misuse-Impacts on the nervous system: An overview.
Clinical applications and side effects of ketamine. Diverse pharmacological
properties of ketamine. Developmental neurotoxicity of ketamine in the
developing brain. Ketamine-Epidemiology of misuse and patterns of acute and
chronic toxicity. Imaging the effects of ketamine use and abuse in the
brain. Does sniffing drugs affect the respiratory system? An example being
ketamine. Long-term ketamine use causes damage to the pancreas and adrenal
glands. Ketamine uropathy: Hong Kong experience. Ketamine and the lower
urinary tract: Summary of pathophysiological evidence in humans and animal
models. Postmortem toxicology of ketamine. The antidepressant effects of
ketamine and the underlying mechanisms. Social correlates of ketamine and
other psychoactive drug abuse in Hong Kong. Mechanisms of ketamine-induced
neuroplasticity: Potential effects on brain and behavior. The influence of
ketamine on our understanding of depression. Clinical testing for ketamine:
How it inspires the need to develop emerging drugs-of-abuse analysis in a
clinical laboratory.