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Now in its second edition, this book covers two major classes of mixed effects models—linear mixed models and generalized linear mixed models—and it presents an up-to-date account of theory and methods in analysis of these models as well as their applications in various fields. It offers a systematic approach to inference about non-Gaussian linear mixed models. Furthermore, it discusses the latest developments and methods in the field, incorporating relevant updates since publication of the first edition. These include advances in high-dimensional linear mixed models in genome-wide association…mehr

Produktbeschreibung
Now in its second edition, this book covers two major classes of mixed effects models—linear mixed models and generalized linear mixed models—and it presents an up-to-date account of theory and methods in analysis of these models as well as their applications in various fields. It offers a systematic approach to inference about non-Gaussian linear mixed models. Furthermore, it discusses the latest developments and methods in the field, incorporating relevant updates since publication of the first edition. These include advances in high-dimensional linear mixed models in genome-wide association studies (GWAS), advances in inference about generalized linear mixed models with crossed random effects, new methods in mixed model prediction, mixed model selection, and mixed model diagnostics.

This book is suitable for students, researchers, and practitioners who are interested in using mixed models for statistical data analysis with public health applications. It is best for graduate courses in statistics, or for those who have taken a first course in mathematical statistics, are familiar with using computers for data analysis, and have a foundational background in calculus and linear algebra.

Autorenporträt
Jiming Jiang is Professor of Statistics and a former Director of Statistical Laboratory at the University of California, Davis. He is a prominent researcher in the fields of mixed effects models, small area estimation, model selection, and statistical genetics. He is the author of Large Sample Techniques for Statistics (Springer 2010), Robust Mixed Model Analysis (2019), Asymptotic Analysis of Mixed Effects Models: Theory, Applications, and Open Problems (2017), and The Fence Methods (with T. Nguyen, 2016). He has been editorial board member of The Annals of Statistics and Journal of the American Statistical Association, among others. He is a Fellow of the American Association for the Advancement of Science, the American Statistical Association, and the Institute of Mathematical Statistics; an elected member of the International Statistical Institute; and a Yangtze River Scholar (Chaired Professor, 2017-2020).

Thuan Nguyen is Associate Professor of Biostatistics in the School of Public Health at Oregon Health & Science University, where she teaches and advises graduate students. She is an active researcher in the field of biostatistics, specializing in the analysis of longitudinal data and statistical genetics, as well as small area estimation. She is the coauthor of The Fence Methods (with J. Jiang 2016).

Rezensionen
From the reviews:

"This book is an up to date description of linear mixed models, LMM, and generalized linear mixed models, GLMM. The material is complete enough to cover a course in a Ph.D. program in statistics. The contribution of this book is that of pointing and developing the inference and estimation issues for non-Gaussion LMMs." (Nicoleta Breaz, Zentrablatt MATH, 2009, 1152)

"The book deals with Gaussian and non-Gaussian linear mixed models. ... This book is suitable for a course in statistics at the MSc level ... . This book contains many examples, exercises and some useful appendices, making it suitable for use in statistics courses. ... The book has a nice lay-out and the index make it easy to jump to a topic of interest. ... A nice feature of the book are the many real-life data examples." (M. Moerbeek, Kwantitatieve Methoden, August, 2007)

"This book, which has grown out of the author's research on this area, deserves close attention. It provides a good reference source for an advanced graduate course and would prove useful for research workers who wish to learn about theoretical developments in this area...[T]his book will be a useful source for obtaining the theoreteical skills required for further developments in this area." (Youngjo Lee, Biometrics, December 2007)

"As noted by the author, there have been many new developments in mixed effects models in the past decade. This volume is intended to provide an up-to-date treatment of both theory and methods. ... it is full of important results and examples, including significant contributions by the author to the treatment of mixed effects models. As a textbook, it is aimed at MS students in statistics, but includes supplementary material more suitable for PhD candidates. ... be useful as such for many GLMM users." (Donald E. Myers, Technometrics, Vol. 50 (1), 2008)

"The book under review covers both LMMs and GLMMs and offersan up-to-date account of theory and methods in the analysis of the models as well as their applications in biological and the medical research, animal and human genetics, and small area estimation. The examples of applications appear near the end of each chapter. ... The book is aimed at students, researchers and other practitioners who are interested in using mixed models for statistical data analysis." (Alexander G. Kukush, Mathematical Reviews, Issue 2007 m)

"Jiming Jiang's book on mixed models covers a lot of material in surprisingly few pages. ... On the whole, it is a rather technical book, both in terms of the mathematical level and in terms of notation ... . Undoubtedly there is a lot one may learn from the book ... . useful for the professional who wishes to know more about the technical results of the topic ... ." (Søren Feodor Nielsen, Journal of Applied Statistics, Vol. 35 (4), 2008)

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