Lipid Signaling and Metabolism (eBook, ePUB)

Redaktion: Ntambi, James M.

• Format: ePub

Produktbeschreibung

Lipid Signaling and Metabolism provides foundational knowledge and methods to examine lipid metabolism and bioactive lipid signaling mediators that regulate a broad spectrum of biological processes and disease states. Here, world-renowned investigators offer a basic examination of general lipid, metabolism, intracellular lipid storage and utilization that is followed by an in-depth discussion of lipid signaling and metabolism across disease areas, including obesity, diabetes, fatty liver disease, inflammation, cancer, cardiovascular disease and mood-related disorders. Throughout, authors demonstrate how expanding our understanding of lipid mediators in metabolism and signaling enables opportunities for novel therapeutics.

Emphasis is placed on bioactive lipid metabolism and research that has been impacted by new technologies and their new potential to transform precision medicine.

• Provides a clear, up-to-date understanding of lipid signaling and metabolism and the impact of recent technologies critical to advancing new studies
• Empowers researchers to examine bioactive lipid signaling and metabolism, supporting translation to clinical care and precision medicine
• Discusses the role of lipid signaling and metabolism in obesity, diabetes, fatty liver disease, inflammation, cancer, cardiovascular disease and mood-related disorders, among others

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 566
• Erscheinungstermin: 9. August 2020
• Englisch
• ISBN-13: 9780128194058
• Artikelnr.: 61689399

Inhaltsangabe

1. Homeostatic Control of Membrane Lipid Biosynthesis in Bacteria
2. Lipid trafficking and signaling in plants
3. Sex as a modulator of lipid metabolism and metabolic disease
4. Local interactions in the bone marrow microenvironment and their
contribution to system metabolic processes
5. Lipids in the Transcriptional Regulation of Adipocyte Differentiation
and Metabolism
6. Lipid receptors and signaling in adipose tissue
7. Adipocyte lipolysis and lipid derived metabolite signaling
8. Regulation of Intracellular Lipid Storage and Utilization
9. The lipid droplet as a signaling node
10. Lipid droplets in the immune response and beyond
11. Fatty acids mediators and the inflammasome
12. Identification and pathophysiological roles of LTB4 receptors BLT1 and
BLT2
13. The Forkhead Box O family in Insulin Action and Lipid Metabolism
14. Interplays between nutritional and inflammatory signaling and fat
metabolism in pathophysiology of NAFLD
15. Endocannabinoids: The Lipid Effectors of Metabolic Regulation in Health
and Disease
16. Gut Microbiota Interaction in Host Lipid Metabolism
17. Insights into the metabolism of lipids in Obesity and Diabetes
18. Lipid metabolic features of skeletal muscle in pathological and
physiological conditions
19. Sphingolipid mediators of cell signaling and metabolism
20. Role of bile acid receptors in the regulation of cardiovascular
diseases
21. Molecular Mechanisms Underlying Effects of n-3 and n-6 Fatty Acids in
Cardiovascular Diseases
22. Lipid metabolism and signaling in Cancer
23. Altered lipid metabolic homeostasis in Alzheimer's disease
24. Role of Xenosterols in Health and Disease
25. Adipose Tissue Development and Metabolic Regulation