Low Density Lipoproteins (eBook, PDF)

Redaktion: Day, Charles

• Format: PDF

Produktbeschreibung

Low density lipoproteins (LDL) are pathophysiologically important be cause of their central role in the disease atherosclerosis and because atherosclerosis is the leading cause of death in developed countries. Many researchers believe that a more detailed knowledge of the struc ture, function, and metabolism of LDL may eventually lead to a means to control atherosclerosis. For this reason a fairly large research effort has gone into the investigation of LDL over the past few years. The purpose of this book is to collect and summarize in one place most of the pub lished information on LDL through 1975. To this end more than 1500 references are cited in the papers that make up this volume. The A, B, C apolipoprotein classification system was adopted for use throughout this work. In addition to the A, B, C, and "D" families of apolipoproteins, apoE is used to designate the "arginine-rich" apolipo protein. This classification system is used because it is far less cumber some than other proposed classification schemes for apolipoproteins.

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Produktdetails

• Verlag: Springer New York
• Seitenzahl: 446
• Erscheinungstermin: 6. Dezember 2012
• Englisch
• ISBN-13: 9781468422504
• Artikelnr.: 43995045

Inhaltsangabe

I. Isolation and Structure.- 1 Isolation and Characterization of Low Density Lipoproteins.- 2 Physicochemical Characterization of Low Density Lipoproteins.- II. Metabolism.- 3 Mechanisms of Formation of Low Density Lipoproteins: Metabolic Pathways and their Regulation.- 4 Interactions of Lipoproteins with Cells in Culture.- 5 Lipoprotein Lipid Exchange in Biological Systems.- 6 Effect of Exercise on Serum Lipids and Lipoproteins.- III. Aberrations of Metabolism.- 7 The Hyper-?- and Hyperpre-?-lipoproteinemias.- 8 Type III Hyperlipoproteinemia.- 9 Lp(a) Lipoproteins and the Genetic Polymorphisms of Lipoprotein B.- 10 Abetalipoproteinemia.- IV. Comparative Biology.- 11 Mammalian Low Density Lipoproteins.- 12 Low Density Lipoproteins of Nonmammalian Vertebrates.- V. Relationship to Atherosclerosis.- 13 Interaction of Low Density Lipoproteins with Arterial Constituents: Its Relationship with Atherogenesis.- 14 Interaction of Low Density Lipoproteins with Small and Large Molecules.- 15 Control of Low Density Lipoproteins and Atherosclerosis with the Bile Acid Sequestrants Colestipol, Cholestyramine, and Polidexide.