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This comprehensive book serves as a guide in the day-to-day management of patients with idiopathic inflammatory myopathies (IIM), with a particular emphasis on adult dermatomyositis (DM), polymyositis (PM), juvenile dermatomyositis, necrotizing myositis, and inclusion body myositis. Practical in nature, it presents IIM concepts in a straightforward fashion, with high-quality figures, algorithms, and flowcharts supplementing each of the expertly authored chapters. The book begins with an introduction to myositis, providing an overview of the myositis basics and what type of patient is affected.…mehr
This comprehensive book serves as a guide in the day-to-day management of patients with idiopathic inflammatory myopathies (IIM), with a particular emphasis on adult dermatomyositis (DM), polymyositis (PM), juvenile dermatomyositis, necrotizing myositis, and inclusion body myositis. Practical in nature, it presents IIM concepts in a straightforward fashion, with high-quality figures, algorithms, and flowcharts supplementing each of the expertly authored chapters. The book begins with an introduction to myositis, providing an overview of the myositis basics and what type of patient is affected. Subsequent chapters are organized by the sequence in which a physician often manages myositis, from initial presentation and workup, to diagnosis, treatment, and finally prognostic and long-term outcome factors. The key differentials in various diagnostic studies are thoroughly examined, including electromyography, muscle biopsy, and MRI. Managing Myositis: A Practical Guide is an easyto-read, indispensable resource for internists, rheumatologists, dermatologists, pulmonologists, and neurologists.
Medical Director, Arthritis and Autoimmunity Center
Co-Director of the UPMC Myositis Center
Pittsburgh, PA 15260
USA
Chester V. Oddis, MD
Professor of Medicine
University of Pittsburgh
School Of Medicine
Director of the Myositis Center
Pittsburgh, PA 15260
USA
Inhaltsangabe
Foreword.- 1 Introduction to Myositis.- 2 Myositis Basics/Who Gets Myositis.- 3 Evaluating the patient with suspected myositis.- 4 Asymptomatic HyperCKemia.- 5 Clinical Features of Myositis Patients: Muscular Manifestations.- 6 Clinical Features of Myositis Patients: Skin Manifestations.- 7 Clinical Features of Myositis Patients: Lung Manifestations.- 8 Clinical Features of Myositis Patients: Cardiac Manifestations.- 9 Clinical Features of Myositis Patients: Juvenile Dermatomyositis clinical features.- 10 Clinical Features of Myositis Patients: Other manifestations: arthritis, Raynaud phenomenon, constitutional.- 11 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Definition and classification of Myositis.- 12 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Electrodiagnostic Testing.- 13 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Muscle biopsy and interpretation.- 14 Making the Diagnosisof Myositis: Beyond the History and Physical Examination: Skin biopsy and interpretation.- 15 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Lung biopsy and interpretation.- 16 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Muscle MRI.- 17 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Laboratory testing in myositis.- 18 Role of ANA and Myositis Autoantibodies in Diagnosis.- 19 Role of Myositis Autoantibodies in Management and Prognosis.- 20 Traditional Myositis Autoantibodies: Synthetase, Mi-2, SRP, Ku, PM-Scl, Ro, U1RNP.- 21 Dermatomyositis-associated Autoantibodies: TIF1-γ, NXP2, and MDA5.- 22 Newly described Myositis Autoantibodies: HMGCR, NT5C1A, SAE, PUF60.- 23 Myositis Mimics: The Differential Diagnosis of Myositis.- 24 Immune Mediated Necrotizing Myopathy (IMNM).- 25 Cancer Associated Myositis.- 26 Myositis Associated Interstitial Lung Disease.- 27 Pregnancy in Myositis.- 28 Pathogenesis of Myositis.- 29 Management Considerations: Pharmacologic intervention.- 30 Management Considerations:Special treatment considerations - JDM.- 31 Management Considerations: Special treatment considerations - Refractory skin rash and calcinosis.- 32 Management Considerations: Special treatment considerations - ILD.- 33 Role of Exercise in the Management of Myositis.- 34 Dietary Considerations in Myositis.- 35 Distinguishing Disease Activity and Damage in Myositis.
Foreword.- 1 Introduction to Myositis.- 2 Myositis Basics/Who Gets Myositis.- 3 Evaluating the patient with suspected myositis.- 4 Asymptomatic HyperCKemia.- 5 Clinical Features of Myositis Patients: Muscular Manifestations.- 6 Clinical Features of Myositis Patients: Skin Manifestations.- 7 Clinical Features of Myositis Patients: Lung Manifestations.- 8 Clinical Features of Myositis Patients: Cardiac Manifestations.- 9 Clinical Features of Myositis Patients: Juvenile Dermatomyositis clinical features.- 10 Clinical Features of Myositis Patients: Other manifestations: arthritis, Raynaud phenomenon, constitutional.- 11 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Definition and classification of Myositis.- 12 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Electrodiagnostic Testing.- 13 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Muscle biopsy and interpretation.- 14 Making the Diagnosisof Myositis: Beyond the History and Physical Examination: Skin biopsy and interpretation.- 15 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Lung biopsy and interpretation.- 16 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Muscle MRI.- 17 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Laboratory testing in myositis.- 18 Role of ANA and Myositis Autoantibodies in Diagnosis.- 19 Role of Myositis Autoantibodies in Management and Prognosis.- 20 Traditional Myositis Autoantibodies: Synthetase, Mi-2, SRP, Ku, PM-Scl, Ro, U1RNP.- 21 Dermatomyositis-associated Autoantibodies: TIF1-Gamma, NXP2, and MDA5.- 22 Newly described Myositis Autoantibodies: HMGCR, NT5C1A, SAE, PUF60.- 23 Myositis Mimics: The Differential Diagnosis of Myositis.- 24 Immune Mediated Necrotizing Myopathy (IMNM).- 25 Cancer Associated Myositis.- 26 Myositis Associated Interstitial Lung Disease.- 27 Pregnancy in Myositis.- 28 Pathogenesis of Myositis.- 29 Management Considerations: Pharmacologic intervention.- 30 Management Considerations:Special treatment considerations - JDM.- 31 Management Considerations: Special treatment considerations - Refractory skin rash and calcinosis.- 32 Management Considerations: Special treatment considerations - ILD.- 33 Role of Exercise in the Management of Myositis.- 34 Dietary Considerations in Myositis.- 35 Distinguishing Disease Activity and Damage in Myositis.
Foreword.- 1 Introduction to Myositis.- 2 Myositis Basics/Who Gets Myositis.- 3 Evaluating the patient with suspected myositis.- 4 Asymptomatic HyperCKemia.- 5 Clinical Features of Myositis Patients: Muscular Manifestations.- 6 Clinical Features of Myositis Patients: Skin Manifestations.- 7 Clinical Features of Myositis Patients: Lung Manifestations.- 8 Clinical Features of Myositis Patients: Cardiac Manifestations.- 9 Clinical Features of Myositis Patients: Juvenile Dermatomyositis clinical features.- 10 Clinical Features of Myositis Patients: Other manifestations: arthritis, Raynaud phenomenon, constitutional.- 11 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Definition and classification of Myositis.- 12 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Electrodiagnostic Testing.- 13 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Muscle biopsy and interpretation.- 14 Making the Diagnosisof Myositis: Beyond the History and Physical Examination: Skin biopsy and interpretation.- 15 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Lung biopsy and interpretation.- 16 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Muscle MRI.- 17 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Laboratory testing in myositis.- 18 Role of ANA and Myositis Autoantibodies in Diagnosis.- 19 Role of Myositis Autoantibodies in Management and Prognosis.- 20 Traditional Myositis Autoantibodies: Synthetase, Mi-2, SRP, Ku, PM-Scl, Ro, U1RNP.- 21 Dermatomyositis-associated Autoantibodies: TIF1-γ, NXP2, and MDA5.- 22 Newly described Myositis Autoantibodies: HMGCR, NT5C1A, SAE, PUF60.- 23 Myositis Mimics: The Differential Diagnosis of Myositis.- 24 Immune Mediated Necrotizing Myopathy (IMNM).- 25 Cancer Associated Myositis.- 26 Myositis Associated Interstitial Lung Disease.- 27 Pregnancy in Myositis.- 28 Pathogenesis of Myositis.- 29 Management Considerations: Pharmacologic intervention.- 30 Management Considerations:Special treatment considerations - JDM.- 31 Management Considerations: Special treatment considerations - Refractory skin rash and calcinosis.- 32 Management Considerations: Special treatment considerations - ILD.- 33 Role of Exercise in the Management of Myositis.- 34 Dietary Considerations in Myositis.- 35 Distinguishing Disease Activity and Damage in Myositis.
Foreword.- 1 Introduction to Myositis.- 2 Myositis Basics/Who Gets Myositis.- 3 Evaluating the patient with suspected myositis.- 4 Asymptomatic HyperCKemia.- 5 Clinical Features of Myositis Patients: Muscular Manifestations.- 6 Clinical Features of Myositis Patients: Skin Manifestations.- 7 Clinical Features of Myositis Patients: Lung Manifestations.- 8 Clinical Features of Myositis Patients: Cardiac Manifestations.- 9 Clinical Features of Myositis Patients: Juvenile Dermatomyositis clinical features.- 10 Clinical Features of Myositis Patients: Other manifestations: arthritis, Raynaud phenomenon, constitutional.- 11 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Definition and classification of Myositis.- 12 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Electrodiagnostic Testing.- 13 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Muscle biopsy and interpretation.- 14 Making the Diagnosisof Myositis: Beyond the History and Physical Examination: Skin biopsy and interpretation.- 15 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Lung biopsy and interpretation.- 16 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Muscle MRI.- 17 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Laboratory testing in myositis.- 18 Role of ANA and Myositis Autoantibodies in Diagnosis.- 19 Role of Myositis Autoantibodies in Management and Prognosis.- 20 Traditional Myositis Autoantibodies: Synthetase, Mi-2, SRP, Ku, PM-Scl, Ro, U1RNP.- 21 Dermatomyositis-associated Autoantibodies: TIF1-Gamma, NXP2, and MDA5.- 22 Newly described Myositis Autoantibodies: HMGCR, NT5C1A, SAE, PUF60.- 23 Myositis Mimics: The Differential Diagnosis of Myositis.- 24 Immune Mediated Necrotizing Myopathy (IMNM).- 25 Cancer Associated Myositis.- 26 Myositis Associated Interstitial Lung Disease.- 27 Pregnancy in Myositis.- 28 Pathogenesis of Myositis.- 29 Management Considerations: Pharmacologic intervention.- 30 Management Considerations:Special treatment considerations - JDM.- 31 Management Considerations: Special treatment considerations - Refractory skin rash and calcinosis.- 32 Management Considerations: Special treatment considerations - ILD.- 33 Role of Exercise in the Management of Myositis.- 34 Dietary Considerations in Myositis.- 35 Distinguishing Disease Activity and Damage in Myositis.
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