Joshua Z. Rappoport

Mapping Humanity (eBook, ePUB)

How Modern Genetics Is Changing Criminal Justice, Personalized Medicine, and Our Identities

• Format: ePub

Produktbeschreibung

"A good companion for those with a science background interested in learning more about human genetics."

Booklist

Thanks to the popularity of personal genetic testing services, it's now easier than ever to get information about our own unique DNAbut who does this information really benefit? And, as genome editing and gene therapy transform the healthcare landscape, what do we gainand what might we give up in return?

Inside each of your cells is the nucleus, a small structure that contains all of the genetic information encoded by the DNA inside, your genome. Not long ago, the first human genome was sequenced at a cost of nearly $3 billion; now, this same test can be done for about $1,000. This new accessibility of genome sequence information creates huge potential for advances in how we understand and treat disease, among other things. It also raises significant concerns regarding ethics and personal privacy.

In Mapping Humanity: How Modern Genetics Is Changing Criminal Justice, Personalized Medicine, and Our Identities, cellular biology expert Joshua Z. Rappoport provides a detailed look at how the explosion in genetic information as a result of cutting-edge technologies is changing our lives and our world.

Inside, discover:

An in-depth look at how your personal genome creates the unique individual that you are

How doctors are using DNA sequencing to identify the underlying genetic causes of disease

Why the field of gene therapy offers amazing potential for medical breakthroughsand why it's taking so long

The fantastic potentialand troubling concernssurrounding genome editing

The real impactand validityof popular personal genetic testing products, such as 23andMe

Details of how molecular biology and DNA are changing the criminal justice system

Facts you should know about Genetically Modified Organisms (GMOs)

Throughout, in compelling, accessible prose, Rappoport explores the societal, ethical, and economic impacts of this new era. Offering a framework for balancing the potential risks and benefits of genetic information technologies and genetic engineering, Mapping Humanity is an indispensable guide to navigating the possibilities and perils of our gene-centric future.

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Produktdetails

• Verlag: Simon + Schuster LLC
• Seitenzahl: 336
• Erscheinungstermin: 7. Juli 2020
• Englisch
• ISBN-13: 9781950665259
• Artikelnr.: 58028708

Autorenporträt

Dr. Joshua Z. Rappoport received a bachelor's degree in Biology from Brown University and then went on to earn a Ph.D. from the Program in Mechanisms of Disease and Therapeutics at the Mount Sinai School of Medicine Graduate School of Biological Sciences of New York University. Following defense of his thesis Dr. Rappoport went on to perform postdoctoral work at The Rockefeller University in New York City in the Laboratory of Cellular Biophysics. Subsequently he was recruited as a tenured faculty member in the School of Biosciences at the University of Birmingham in England. In 2014 Dr. Rappoport has returned to the United States where he is currently the Director of the Center for Advanced Microscopy and Nikon Imaging Center at the Northwestern University Feinberg School of Medicine, and a faculty member in the Department of Molecular and Cell Biology. Dr. Rappoport's scientific perspective aims to develop and apply cutting edge microscopy to address fundamental questions in cell biology. Dr. Rappoport lives in Chicago with his wife Ema, a neuroscientist, and their dog Kris.

Inhaltsangabe

Contents
Introduction Part I: The Human Genome 101 Chapter 1: The Basics of DNA,
Chromosomes, and Genes Chapter 2: Gene Mutations and Polymorphisms Part II:
DNA Sequencing Methods Chapter 3: Sequencing DNA Chapter 4: Next-Generation
Sequencing Chapter 5: Big Data! Part III: Applications for Genomic
Information Chapter 6: Ancestry Chapter 7: Neanderthal DNA Chapter 8:
Genetic Screening Chapter 9: Genomic Justice Chapter 10: Classical Methods
to Search for Disease-Causing Mutations Chapter 11: Genome-Wide Association
Studies Chapter 12: Twenty-First Century Eugenics? Chapter 13: DNA and
Prenatal Genetic Testing Chapter 14: Pharmacogenomics Chapter 15:
Personalized Medicine Chapter 16: Gene Therapy Part IV: Genetic Engineering
Chapter 17: CRISPR-Clustered Regularly Interspaced Short Palindromic
Repeats Chapter 18: CRISPR Babies? Chapter 19: GMOs-Genetically Modified
Organisms Chapter 20: The Future of Food? Chapter 21: Pets-Ancestry,
Health, and Cloning Chapter 22: Conservation and Eradication Part V: Beyond
the Genome Chapter 23: The Basics of Epigenetics Chapter 24: Epigenetics in
Action Chapter 25: Mitochondrial DNA Chapter 26: The Future
References Index Acknowledgments About the Author