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Assembling the work of an international panel of researchers, this volume summarizes and reviews the latest developments in the field of nucleic acid research by mass spectrometry and provides a window on the next generation of analysis. It highlights the most popular ionization methods and illustrates the diverse strategies used in the characterization and sequencing of novel nucleosides and nucleotides. It also covers deoxyribonucleic acid (DNA), DNA-adducts, DNA-drug complexes, ribonucleic acid (RNA) oligomers of biomedical importance, RNA-protein complexes, and post-transcriptional…mehr

Produktbeschreibung
Assembling the work of an international panel of researchers, this volume summarizes and reviews the latest developments in the field of nucleic acid research by mass spectrometry and provides a window on the next generation of analysis. It highlights the most popular ionization methods and illustrates the diverse strategies used in the characterization and sequencing of novel nucleosides and nucleotides. It also covers deoxyribonucleic acid (DNA), DNA-adducts, DNA-drug complexes, ribonucleic acid (RNA) oligomers of biomedical importance, RNA-protein complexes, and post-transcriptional modifications. The contributions presented in this volume capture the range of these advances, helping to inspire new findings and avenues of research.

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Autorenporträt
Joseph H. Banoub is a principal scientist and head of the special projects at Fisheries and Oceans Canada, Science Branch. He has been an adjunct professor of biochemistry at Memorial University of Newfoundland since 1984 and an adjunct professor of chemistry since 2006. His present research interests include the uses of tandem mass spectrometry for the structural elucidation of biologically active molecules. Patrick A. Limbach is a professor of chemistry and department head at the University of Cincinnati. His research interests include the development of new mass spectrometry methods for analyzing RNAs, the identification of unknown modified nucleosides, the characterization of RNA-protein complexes, and investigating the role of modified nucleosides in biological systems.