Medicinal Chemistry of Chemotherapeutic Agents (eBook, ePUB)

A Comprehensive Resource of Anti-infective and Anti-cancer Drugs
Redaktion: Acharya, Pratap Chandra; Kurosu, Michio

• Format: ePub

Produktbeschreibung

Medicinal Chemistry of Chemotherapeutic Agents: A Comprehensive Resource of Anti-infective and Anti-cancer Drugs focuses on the basics and fundamentals of chemistry involved in chemotherapeutic agents. Each chapter comprises distinct chemical classifications that include structure and IUPAC nomenclature, synthetic schemes and routes for each drug, mechanism of the drug action, metabolic pathway and structure-activity relationship (SAR) studies. The book covers current research focused on drug resistance and methods to overcome it, the development of newer drugs belonging to each category of the chemotherapeutic agents, molecules currently under clinical trials, and newly approved drugs, if any.

This book will be a valuable resource for academics and researchers, helping them to understand the fundamentals of the medicinal chemistry of the chemotherapeutic agents.

• Includes current research focused on drug resistance and methods to overcome problems
• Outlines synthetic schemes and metabolic pathways of chemotherapeutic agents
• Discusses molecules under clinical trials and newly approved drugs

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 686
• Erscheinungstermin: 9. März 2023
• Englisch
• ISBN-13: 9780323907019
• Artikelnr.: 67592870

Inhaltsangabe

1. Introduction to Chemotherapy: General and Clinical Considerations
Section A. ANTIMICROBIAL AGENTS Unit I Antibacterial Agents 2.
Sulfonamides, Quinolones, Antiseptics and Disinfectants Unit II
Antibacterial Antibiotics 3. Beta-Lactam Antibiotics: Penicillins,
Cephalosporins, Monobactams, Carbapenems and Beta-lactamase Inhibitors 4.
Tetracyclines and Chloramphenicol 5. Aminoglycoside Antibiotics 6.
Macrolide, Lincosamide, Glycopeptide and Other Antibacterial Antibiotics
Unit III Antimycobacterial Agents 7. Antitubercular Drugs 8. Antileprotic
Drugs Unit IV Antifungal Agents 9. Topical and Systemic Antifungal Drugs
Unit V Antiviral Agents 10. Antiviral Drugs and Vaccines Unit VI
Antiprotozoal Agents 11. Antimalarial Drugs 12. Antiamoebic Drugs 13. Drugs
for Giardiasis, Trichomoniasis and Leishmaniasis UNIT VII Anthelmintics
14. Vermifuge and Vermicide Drugs
Section B ANTINEOPLASTIC AGENTS 15. Synthetic Cytotoxic Drugs as Cancer
Chemotherapeutic Agents 16. Naturally Occurring Anticancer Cytotoxic Drugs
17. Hormones and Antihormones in Cancer Chemotherapy 18. Biologicals and
Small Molecules as Target Specific Cancer Chemotherapeutic Agents