Metalloenzymes (eBook, ePUB)

From Bench to Bedside
Redaktion: Supuran, Claudiu T.; Donald, William Alexander

• Format: ePub

Produktbeschreibung

Metalloenzymes: From Bench to Bedside offers a thorough overview of metalloenzymes, spanning biochemical and structural features, pharmacology, and biotechnological applications. After a brief overview, international experts in the field discuss a wide range of magnesium, calcium, zinc, manganese, nickel, iron, copper, cadmium, molybdenum, and tungsten enzymes, along with catalytic roles within their active sites. With a uniform approach throughout, each chapter includes the structure and function of the enzyme, physiologic and pathologic roles, inhibitors and activators of the enzyme (and their design), and clinical agents or compounds applied in medicine and drug discovery. This book enables scientists across academia and industry to adopt ongoing metalloenzyme research, and continuous discovery of novel metalloenzymes, in new life science studies and clinical applications.

• Examines a range of metalloenzymes, from biochemistry to pharmacology and drug design
• Each chapter examines enzyme structure and function, physiologic and pathologic roles, inhibitors and activators, and clinical application
• Features chapter contributions from international experts in the field

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 464
• Erscheinungstermin: 30. August 2023
• Englisch
• ISBN-13: 9780128242353
• Artikelnr.: 68788458

Inhaltsangabe

1. Introduction to metalloenzymes
Section II 2. Magnesium and calcium-containing enzymes
Section III 3. Zinc enzymes
Section IV. Other metalloenzymes 4. Manganese enzymes 5. Nickel enzymes 6.
Iron enzymes (heme-containing) 7. Iron enzymes (non-heme containing, Fe(II)
or Fe(III) proteins) 8. Copper enzymes 9. Cadmium enzymes 10. Molybdenum
enzymes 11. Tungsten-containing enzymes