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The study of proteomics provides researchers with a better understanding of disease and physiological processes in animals. Methods in Animal Proteomics will provide animal scientists and veterinarians currently researching these topics in domestic animals a firm foundation in the basics of proteomics methodology, while also reviewing important advances that will be of interest to established researchers in the field. Chapters will provide practical information on a range of topics including protein identification and separation, bioinformatics, and applications to disease and reproduction…mehr
The study of proteomics provides researchers with a better understanding of disease and physiological processes in animals. Methods in Animal Proteomics will provide animal scientists and veterinarians currently researching these topics in domestic animals a firm foundation in the basics of proteomics methodology, while also reviewing important advances that will be of interest to established researchers in the field. Chapters will provide practical information on a range of topics including protein identification and separation, bioinformatics, and applications to disease and reproduction research. This text will be written by leading international proteomics experts and essential for researchers in the fields of animal biology and veterinary medicine.
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Autorenporträt
Philip D. Whitfield is Head of Lipodomic Research at the University of the Highlands and Islands Department of Diabetes and Cardiovascular Science David Eckersall is Professor of Veterinary Biochemistry University of Glasgow.
Inhaltsangabe
Contributors vii Acknowledgments xi Section 1: Exploring Animal Proteomes 3 1 An Introduction to Animal Proteomics 5 Phillip D. Whitfield and P. David Eckersall 2 Types of Sample and Experimental Planning 11 Christine Olver 3 Protein Separation Strategies 41 Ingrid Miller 4 Methods and Approaches to Mass Spectroscopy-Based Protein Identification 77 John D. Lippolis and Timothy A. Reinhardt 5 Bioinformatics in Animal Proteomics 103 Paul Blakeley, James C. Wright, Simon J. Hubbard, and Andrew R. Jones 6 Comparative Proteomic Approaches 121 Johanna S. Rees and Kathryn S. Lilley 7 Advancing Technologies for Spatial and Temporal Proteomics 159 Mary Doherty Section 2: Applications of Proteomics in Animal Biology 189 8 Proteomic Strategies to Investigate Adaptive Processes 191 L. Elaine Epperson and Sandra L. Martin 9 Investigation of Animal Venoms and Toxins 211 Stephen McClean 10 Proteomics in Animal Health and Disease 243 P. David Eckersall and Mark McLaughlin 11 Application of Proteomics to Elucidate Bacterium-Host Interactions 319 David G.E. Smith 12 Animal Parasitology and Proteomics 349 Richard Burchmore 13 Proteomics in Animal Reproduction and Breeding 369 Divyaswetha Peddinti, Erdogan Memili, and Shane C. Burgess 14 Assessment in the Quality and Safety of Food of Animal Origin 397 Begonya Marcos, Jingshun Liu, Dilip K. Rai, Alessio Di Luca, and Anne Maria Mullen Index 431
Contributors vii Acknowledgments xi Section 1: Exploring Animal Proteomes 3 1 An Introduction to Animal Proteomics 5 Phillip D. Whitfield and P. David Eckersall 2 Types of Sample and Experimental Planning 11 Christine Olver 3 Protein Separation Strategies 41 Ingrid Miller 4 Methods and Approaches to Mass Spectroscopy-Based Protein Identification 77 John D. Lippolis and Timothy A. Reinhardt 5 Bioinformatics in Animal Proteomics 103 Paul Blakeley, James C. Wright, Simon J. Hubbard, and Andrew R. Jones 6 Comparative Proteomic Approaches 121 Johanna S. Rees and Kathryn S. Lilley 7 Advancing Technologies for Spatial and Temporal Proteomics 159 Mary Doherty Section 2: Applications of Proteomics in Animal Biology 189 8 Proteomic Strategies to Investigate Adaptive Processes 191 L. Elaine Epperson and Sandra L. Martin 9 Investigation of Animal Venoms and Toxins 211 Stephen McClean 10 Proteomics in Animal Health and Disease 243 P. David Eckersall and Mark McLaughlin 11 Application of Proteomics to Elucidate Bacterium-Host Interactions 319 David G.E. Smith 12 Animal Parasitology and Proteomics 349 Richard Burchmore 13 Proteomics in Animal Reproduction and Breeding 369 Divyaswetha Peddinti, Erdogan Memili, and Shane C. Burgess 14 Assessment in the Quality and Safety of Food of Animal Origin 397 Begonya Marcos, Jingshun Liu, Dilip K. Rai, Alessio Di Luca, and Anne Maria Mullen Index 431
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