Mixture Toxicity (eBook, PDF)

Linking Approaches from Ecological and Human Toxicology
Redaktion: Gestel, Cornelis A. M. van; Svendsen, Claus; Laskowski, Ryszard; Kammenga, Jan E.; Jonker, Martijs

• Format: PDF

Produktbeschreibung

Although the fields of toxicology and human health assessment address similar problems, the experts from these fields do not meet very frequently. Originating from a meeting of scientists in both fields, this book clearly links ecotoxicology and classic human toxicology. It incorporates extensive reviews of exposure to toxicants, toxicokinetics and toxicodynamics, toxicology of mixtures, and risk assessment. This unusual combination of coverage sets it apart from other ecotoxicological and risk assessment resources that do not discuss these topics in an integrated manner.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 320
• Erscheinungstermin: 19. April 2016
• Englisch
• ISBN-13: 9781439830093
• Artikelnr.: 57534264

Autorenporträt

van Gestel, Cornelis A. M.; Jonker, Martijs; Kammenga, Jan E.; Laskowski, Ryszard; Svendsen, Claus

Inhaltsangabe

Exposure. Introduction. Emission Scenarios. Interactions Affecting
Availability and Exposure to Chemical Mixtures. Environmental Fate
Modeling. Exposure Scenarios and Monitoring. Summary and Conclusions.
Toxicokinetics and Toxicodynamics. Introduction. Fundamental Principles.
Toxicokinetics. Toxicodynamics. Toxicity from Combined Exposure to
Chemicals. Introduction. Approaches to Mixture Effect Assessment.
Mechanisms and mixture effects. The predictability of mixture effects - a
brief review. Defining Determinants of Synergistic Mixture Effects. Mixture
Effects at Low Levels. What About the Real World? Test Design, Mixture
Characterization and Data Evaluation. Introduction. Testing Aims.
Concentration Addition and Independent Action: Empirical Modeling.
Technical Issues and Pitfalls. Component-Based Approaches, Test Designs and
Methods. Whole Mixture Approaches, Test Designs and Methods. Case Studies.
Risk Assessment. Introduction. Typical Features of Mixture Assessment.
State of the Art in Mixture Assessment. Conceptual Framework for Human and
Ecological Risk Assessment of Mixtures. Issues in Human and Ecological Risk
Assessment of Mixtures. Appendix. Glossary.