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  • Format: ePub

This book on modeling and simulating cardiac electrophysiology provides a thorough introduction to the topic of mathematical modeling of electrical activity in the heart. It discusses how cellular ionic models are formulated, introduces commonly used models and explains why there are so many different models available. Individual chapters are provided by authors who are experts in their fields and describe modeling of the intracellular calcium handling that underlies cellular contraction as well as modeling molecular-level details of cardiac ion channels.
Additional chapters focus on more
…mehr

Produktbeschreibung
This book on modeling and simulating cardiac electrophysiology provides a thorough introduction to the topic of mathematical modeling of electrical activity in the heart. It discusses how cellular ionic models are formulated, introduces commonly used models and explains why there are so many different models available. Individual chapters are provided by authors who are experts in their fields and describe modeling of the intracellular calcium handling that underlies cellular contraction as well as modeling molecular-level details of cardiac ion channels.

Additional chapters focus on more specialized topics such as cardiomyocyte energetics and signalling pathways. The book covers general principles of tissue modeling and provides examples of clinical translation by development of patient-specific mathematical models.

Aimed towards readers with a background in the biological sciences, who do not necessarily have much training in mathematical modeling and computational methods, the book is also a useful resource for the more experienced researchers on specialized topics that are tightly coupled to the electrophysiology of the heart.


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