Molecular Basis of Sex Hormone Receptor Function (eBook, PDF)

New Targets for Intervention
Redaktion: Gronemeyer, Hinrich; Parczyk, Karsten; Fuhrmann, Ulrike

• Format: PDF

Produktbeschreibung

Ernst Schering Research Foundation Workshop 24 Molecular Basis of Sex Hormone Receptor Function Editors: H. Gronemeyer, U. Fuhrmann, K. Parczyk How sex hormone receptors and all of the other members of the nuclear receptor superfamily can do such a remarkable job has fascinated scientists for decades. A series of discoveries in the past few years has dramatically enlightened our understanding of the molecular mechanisms that govern nuclear receptor action. The Ernst Schering Research Foundation Workshop 24 presents the latest findings and current view of the "Molecular basis of sex hormone receptor function".

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Produktdetails

• Verlag: Springer Berlin Heidelberg
• Seitenzahl: 238
• Erscheinungstermin: 17. April 2013
• Englisch
• ISBN-13: 9783662036891
• Artikelnr.: 53086122

Inhaltsangabe

1 Nuclear Receptors as Targets for Drug Design: New Options and Old Challenges.- 2 The Androgen Receptor Co-regulator, ARA70.- 3 Role of Coactivators in Transcriptional Activation by Estrogen Receptors.- 4 A Search for a Mechanism for the Antiinflammatory Action of Glucocorticoids.- 5 Activation of Progesterone and Androgen Receptors by Signal Transduction Pathways.- 6 Ligand-Independent Activation of the Estrogen Receptor: Activation by Epidermal Growth Factor and Dopamine.- 7 The ER/AP1 Pathway: A Window on the Cell-Specific Estrogen-like Effects of Antiestrogens.- 8 A Structural View of the Retinoid Nuclear Receptors.- 9 Characterization of Human Estrogen Receptorß.- 10 Functional and Pharmacological Analysis of the A and B Forms of the Human Progesterone Receptor.- 11 Oestrogen Receptor Expression Mutants and Variants in Tamoxifen-Resistant Breast Cancer.- 12 Structure and Expression of the Androgen Receptor in Prostate Cancer.- Previous Volumes Published in this Series.