David P. Clark, Nanette J. Pazdernik

Molecular Biology (eBook, ePUB)

• Format: ePub

Produktbeschreibung

Molecular Biology, Second Edition, introduces the basic concepts of molecular biology while incorporating primary literature from today's leading researchers. This new edition reflects the massive surge in our understanding of the molecular foundations of genetics, thanks to major scientific revolutions in genetics and computer technology. It explains how living organisms function at a molecular level and how DNA, RNA, and proteins interact to provide the cell with genetic information.

This volume goes far beyond the flowing text, annotation, and hyperlinking available in most ebooks. Unique features include interactive quizzes for enhanced student understanding and self-testing; narrated animations to clarify complex content; and study guides equipped with 62 full-text Cell Press journal articles, all in one downloadable package. Also new to this second edition are updated chapters on genomics and systems biology, proteomics, bacterial genetics, and molecular evolution and RNA. A fully revised art completes the updates made in this ebook.

This book will be of interest to undergraduate students taking a course in Molecular Biology, as well as upper-level students studying Cell Biology, Microbiology, Genetics, Biology, Pharmacology, Biotechnology, Biochemistry and Agriculture.

• Winner of a 2013 Texty Award from the Text and Academic Authors Association
• Includes interactive elements for enhanced student understanding and self-testing; animations to clarify complex content; and study guides equipped with full-text Cell Press journal articles
• New to second edition: updated chapters on genomics and systems biology; proteomics; bacterial genetics; and molecular evolution and RNA
• Fully revised art

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 928
• Erscheinungstermin: 10. Juli 2013
• Englisch
• ISBN-13: 9780124105171
• Artikelnr.: 38395097

Autorenporträt

David P. Clark did his graduate work on bacterial antibiotic resistance to earn his Ph.D. from Bristol University, England. He later crossed the Atlantic to work as a postdoctoral researcher at Yale University and then the University of Illinois. Dr Clark recently retired from teaching Molecular Biology and Bacterial Physiology at Southern Illinois University which he joined in 1981. His research into the Regulation of Alcohol Fermentation in E. coli was funded by the U.S. Department of Energy, from 1982 till 2007. In 1991 he received a Royal Society Guest Research Fellowship to work at Sheffield University, England while on sabbatical leave.

Inhaltsangabe

Unit 1: Basic Chemical and Biological Principles 1. Cells and Organisms 2. Basic Genetics 3. DNA, RNA, and Protein 4. Genes, Genomes, and DNA 5. Manipulation of Nucleic Acids

Unit 2: The Genome 6. The Polymerase Chain Reaction 7. Cloning Genes for Analysis 8. DNA Sequencing 9. Genomics and Systems Biology New Chapter to cover metagenomics, symbiosis, epigenomics etc

Unit 3: The Central Dogma of Molecular Biology 10. Cell Division and DNA Replication 11. Transcription of Genes 12. Processing of RNA (moved to Unit 4) 13. Protein Synthesis 14. Protein Structure and Function 15. Proteomics: Global Analysis of Proteins

Unit 4: Regulating Gene Expression 16. Regulation of Transcription in Prokaryotes 17. Regulation of Transcription in Eukaryotes 12. Processing of RNA (moved from Unit 3) 18. Regulation at the RNA Level New Chapter on Genome defense (RNAi and CRISPR). Would include their use in genetic analysis and genome editing 19. Analysis of Gene Expression (Transcriptome)

Unit 5: Subcellular Life Forms 20. Plasmids 21. Viruses 22. Mobile DNA

Unit 6: Changing the DNA Blueprint 23. Mutations and Repair 24. Recombination 25. Bacterial Genetics 26. Molecular Evolution