Molecular Mechanisms of Fanconi Anemia (eBook, PDF)

Redaktion: Ahmad, Shamim; Kirk, Sandra

• Format: PDF

Produktbeschreibung

This book provides the only comprehensive treatise available on Fanconi Anemia. It gives a detailed analysis from the clinical to the molecular levels of the disorder. It also allows insight into the mechanisms of responses to DNA damage, and the complex interactions of several previously unknown proteins. The book will give research students a platform for further investigation, and act as a source of information regarding experimental design.

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Produktdetails

• Verlag: Springer US
• Seitenzahl: 121
• Erscheinungstermin: 6. März 2007
• Englisch
• ISBN-13: 9780387337760
• Artikelnr.: 37288581

Autorenporträt

Shamin Ahmad, Trent University, Nottingham, UK / Sandra Kirk, Trent University, Nottingham, UK

Inhaltsangabe

Clinical Features of Fanconi Anaemia.- The Genetic Basis of Fanconi Anemia.- The FANCA Gene and Its Products.- The FANCC Gene and Its Products.- The FANC B, E, F and G Genes and Their Products.- FANCD1/BRCA2 and FANCD2.- The FANC Genome Surveillance Complex.- Other Proteins and Their Interactions with FA Gene Products.- Fanconi Anaemia and Oxidative Stress.- Therapy for Fanconi Anemia.- Mutational Analyses of Fanconi Anemia Genes in Japanese Patients.