NanoparticleProtein Corona (eBook, PDF)

Biophysics to Biology
Redaktion: Kumar, Ashutosh; Dhawan, Alok

• Format: PDF

Produktbeschreibung

Nanoparticles have numerous biomedical applications including drug delivery, bone implants and imaging. A protein corona is formed when proteins existing in a biological system cover the nanoparticle surface. The formation of a nanoparticle-protein corona, changes the behaviour of the nanoparticle, resulting in new biological characteristics and influencing the circulation lifetime, accumulation, toxicity, cellular uptake and agglomeration.

This book provides a detailed understanding of nanoparticle-protein corona formation, its biological significance and the factors that govern the formation of coronas. It also explains the impact of nanoparticle-protein interactions on biological assays, ecotoxicity studies and proteomics research. It will be of interest to researchers studying the application of nanoparticles as well as toxicologists and pharmaceutical chemists.

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Produktdetails

• Verlag: Royal Society of Chemistry
• Seitenzahl: 293
• Erscheinungstermin: 26. Juli 2019
• Englisch
• ISBN-13: 9781788016308
• Artikelnr.: 70074451

Inhaltsangabe

Nanoparticle-Protein Corona Complex: Composition, Kinetics,
Physico-Chemical Characterization, and Impact on Biomedical Applications;
Biological Significance of the Nanoparticles Protein Corona; Factors
Affecting a Nanoparticle's Protein Corona Formation; NP-Protein Corona
Interaction: Characterization Methods and Analysis; An Analytical Approach
to Investigate Nanoparticle-Protein Corona Complexes; Impact of
Nanoparticle-Protein Interactions on Biological Assays; Computer
Simulations for Understanding Nanoparticle-biomolecule Corona Formation; In
Silico Approaches to Design and Characterize Peptide-based Nanostructures;
Nanomaterial-Blood Interactions: A Biomedical Perspective; The Protein
Corona: Applications and Challenges