Natural compounds as inducers of cell death (eBook, PDF)

volume 1
Redaktion: Diederich, Marc; Noworyta, Karoline

• Format: PDF

Produktbeschreibung

The content of this book gives a multi-disciplinary approach into the anti-cancer research field related to natural products and dietary compounds. Mainly, it covers the area of antitumor activity through an in-depth description of the cytotoxic, anti-inflammatory and anti-oxidant properties in cancer, inflammatory and cardio-vascular diseases. The cell death inducing mechanisms (apoptosis, anti-proliferative activity, angiogenesis, cell cycle control, cytostatic property and autophagy) give an overview of how natural products are able to target cancer cells.

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Produktdetails

• Verlag: Springer Netherlands
• Seitenzahl: 518
• Erscheinungstermin: 31. August 2012
• Englisch
• ISBN-13: 9789400745759
• Artikelnr.: 37805864

Inhaltsangabe

Section 1, Phytochemicals as inducers of cell death mechanisms.- 1. Phytochemicals and Amino Acids: Inducers or Inhibitors of Cell Death?.- 2. Pomegranate-derived constituents as inducers of cell death: implications in cancer prevention and therapy.- 3. Antitumor effects of anthocyanins: focus on apoptosis.- 4. Anti-proliferative and apoptosis-inducing properties of Xanthohumol, a prenylated chalcone from hops (Humulus lupulus L.).- 5. Bioavailabitility and Metabolism of Curcuminoids. Section 2, Natural compounds from animal origins.- 6. Melatonin in cell fate decisions: mechanistic perspectives and therapeutical potential.- 7. Pharmacologically active compounds from ticks and other arthropods and their potential use in anticancer therapy. Section 3, Polyphenols as inducers of cell death.- 8. Induction of Apoptosis by Polyphenolic Compounds in Cancer Cells.- 9. Encapsulation of natural polyphenols with antioxidant properties in polyelectrolyte capsules and nanoparticles.- 10. Inductionof Cell Death Occurring with Autophagy by Polyphenolic Compounds in Cancer.- Section 4, Redox active natural compounds.- 11. Total antioxidant capacity: a useful tool in assessing antioxidant intake status.- 12. Natural sulfur products as redox modulators and selective inducers of cell death.- 13. Diallyl sulfides and the decision about life and death of a cell.- Section 5, Effect of natural compounds on cell cell signaling pathways.- 14. Natural compounds as specific inhibitors of cyclin-dependent kinases - past, present and future.- 15. Plant-derived isoprenoids mediate regulation of mTOR signaling in tumor cells.- 16. Regulation of MicroRNAs by Natural Compounds: Implications for Cancer Therapy.- Section 6, Phytochemicals in inflammation and cancer.- 17. Interference with estrogen receptor- by dietary components: impact on the balance between cell proliferation and cell death.- 18. Natural Triterpenoids from Olive Oil: Potential Activities Against Cancer.- 19. Dietary sources of natural inducers of cell death: considerations for cancer therapy and prevention.- Section 7, Phytochemicals in health and disease.- 20. Tocotrienols in the control of pathological fibroinflammatory processes.- 21. Anthocyanins: Janus nutraceuticals displaying chemotherapeutic and neuroprotective properties.- Index.