Natural Compounds as Therapeutic Agents for Amyloidogenic Diseases (eBook, PDF)

Redaktion: Vassallo, Neville

• Format: PDF

Produktbeschreibung

This edited volume concerns a group of devastating neurological disorders that share a common pathological mechanism, namely the aggregation and deposition of insoluble, proteinaceous lesions, termed 'amyloid'. Examples of cerebral amyloid disorders include common neurodegenerative diseases like Alzheimer's disease-related dementia and Parkinson's disease, as well as other less prevalent conditions like Huntington's disease, cerebral amyloid angiopathy and the transmissible prion disorders. A disease-modifying therapeutic agent is still lacking for all these diseases, and there are no approved therapies that target amyloid formation directly. Nevertheless, a large and complex group of natural aromatic compounds known as polyphenols are rapidly emerging as potentially potent anti-amyloidogenic agents.

This book collectively presents a considerable body of experimental and epidemiological evidence from peer-reviewed scientific publications that support a role for natural compounds and herbal extracts in the chemoprevention and therapy of amyloidogenic disorders.

Each contribution is written by scientific experts in the relevant field; chapters are devoted to Mediterranean diet and olive oil phenols, traditional Chinese medicine, herbal extracts, polyphenols (with a particular emphasis on epigallocatechin-3-gallate) and bi-flavonoids, amongst others.

The topic of this book is relevant to a wide audience, from academia and university students in the biological and chemical sciences, to physicians and allied health professionals, as well as people working in the nutraceutical industry.

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Produktdetails

• Verlag: Springer Nature Switzerland
• Seitenzahl: 163
• Erscheinungstermin: 19. Juni 2015
• Englisch
• ISBN-13: 9783319183657
• Artikelnr.: 43787069

Inhaltsangabe

Olive Oil Phenols as Promising Multi-targeting Agents against Alzheimer's disease.- Alzheimer's disease, Drosophila melanogaster and Polyphenols.- Biflavonoids as Potential Small Molecule Therapeutics for Alzheimer's disease.- Natural Phenolic Compounds as Therapeutic and Preventive Agents for Cerebral Amyloidosis.- Brain Food for Alzheimer-free Ageing: Focus on Herbal Medicines.- Tea Polyphenols in Parkinson's disease.- The Effect of (-)-Epigallo-catechin-(3)-gallate on Amyloidogenic Proteins Suggests a Common Mechanism.