Nature's Gift to Neuroscience (eBook, PDF)

A Tribute to Sydney Brenner and John Sulston
Redaktion: Wu, Chun-Fang; Alcedo, Joy

• Format: PDF

Produktbeschreibung

As a tribute to Sydney Brenner and John Sulston, this book captures the perspectives of some of the early pioneers of the worm community, from Martin Chalfie, Robert Waterston and Donald Moerman to Catherine Rankin, Antony Stretton and John White.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 372
• Erscheinungstermin: 27. Februar 2022
• Englisch
• ISBN-13: 9781000566413
• Artikelnr.: 63518486

Autorenporträt

Chun-Fang Wu is Editor-in-Chief of the Journal of Neurogenetics. He has conducted neurobiological research in Drosophila, applying genetic, cell biological, physiological, and behavioural techniques in the studies. Joy Alcedo is Guest Editor for the C. elegans special issue of the Journal of Neurogenetics. Her research focuses on the sensory and neuromodulatory influences on C. elegans development and survival programs.

Inhaltsangabe

Introduction: Nature's gift to neuroscience Part 1: The early years of C.
elegans neurogenetics 1. My life with Sydney, 1961-1971 2. John Sulston
(1942-2018): a personal perspective 3. A touching story 4. But can they
learn? My accidental discovery of learning and memory in C. elegans 5. Of
worms and men Part 2: Nervous system development 6. A perspective on C.
elegans neurodevelopment: from early visionaries to a booming neuroscience
research 7. Neuronal specification in C. elegans: combining lineage
inheritance with intercellular signaling 8. Molecular mechanisms governing
axonal transport: a C. elegans perspective 9. C. elegans MAGU-2/Mpp5
homolog regulates epidermal phagocytosis and synapse density 10. Synaptic
remodeling, lessons from C. elegans 11. What about the males? the C.
elegans sexually dimorphic nervous system and a CRISPR-based tool to study
males in a hermaphroditic species 12. Cell-type-specific promoters for C.
elegans glia Part 3: From inputs to outputs 13. C. elegans: a sensible
model for sensory biology 14. Temperature signaling underlying thermotaxis
and cold tolerance in Caenorhabditis elegans 15. Mechano-gated channels in
C. elegans 16. What can a worm learn in a bacteria-rich habitat? 17. C.
elegans aversive olfactory learning generates diverse intergenerational
effects Part 4: Social and sexual behaviors 18. Social and sexual behaviors
in C. elegans: the first fifty years 19. Small molecule signals mediate
social behaviors in C. elegans 20. Intraguild predation between
Pristionchus pacificus and Caenorhabditis elegans: a complex interaction
with the potential for aggressive behaviour 21. Plasticity of
pheromone-mediated avoidance behavior in C. elegans Part 5: Quiescence and
sleep 22. Worms sleep: a perspective 23. Cellular damage, including
wounding, drives C. elegans stress-induced sleep 24. Orcokinin
neuropeptides regulate sleep in Caenorhabditis elegans 25. Discriminating
between sleep and exercise-induced fatigue using computer vision and
behavioral genetics 26. The OptoGenBox - a device for long-term
optogenetics in C. elegans Part 6: Survival, aging and disease 27.
Neuromodulators: an essential part of survival 28. Neuroendocrine control
of lipid metabolism: lessons from C. elegans 29. The discovery and
consequences of the central role of the nervous system in the control of
protein homeostasis 30. Host-microbe interactions and the behavior of
Caenorhabditis elegans 31. Neurogenetics of nictation, a dispersal strategy
in nematodes 32. Regulatory systems that mediate the effects of temperature
on the lifespan of Caenorhabditis elegans 33. The contribution of C.
elegans neurogenetics to understanding neurodegenerative diseases Part 7:
Worm photo and art gallery 34. A journey to 'tame a small metazoan
organism', seen through the artistic eyes of C. elegans researchers