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The field of neuroimaging genetics has grown exponentially over the past decade. To date there are more than 10,000 published papers involving MRI, PET, MEG and genetics. Neuroimaging Genetics: Principles and Practices is the comprehensive volume edited by Drs. Bigos, Hariri, and Weinberger and co-authored by the preeminent scholars in the field. This text reviews the basic principles of neuroimaging techniques and their application to neuroimaging genetics. The work presented in this volume elaborates on the explosive interest from diverse research areas in psychiatry and neurology in the use…mehr
The field of neuroimaging genetics has grown exponentially over the past decade. To date there are more than 10,000 published papers involving MRI, PET, MEG and genetics. Neuroimaging Genetics: Principles and Practices is the comprehensive volume edited by Drs. Bigos, Hariri, and Weinberger and co-authored by the preeminent scholars in the field. This text reviews the basic principles of neuroimaging techniques and their application to neuroimaging genetics. The work presented in this volume elaborates on the explosive interest from diverse research areas in psychiatry and neurology in the use of imaging genetics as a unique tool to establish and identify mechanisms of risk, establish biological significance, and extend statistical evidence of genetic associations. Examples throughout highlight the application of imaging genetics to understand neurochemical systems and pathways, explore relationships between genetics and the structural and functional connectivity in human brain, and provide insight into mechanisms of risk for psychiatric and neurologic illness.
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Autorenporträt
Kristin L. Bigos is an Investigator in the Division of Clinical Pharmacology at the Lieber Institute for Brain Development; Ahmad R. Hariri is a Professor in the Departments of Psychology and Neuroscience at Duke University; Daniel R. Weinberger is Director and CEO of the Lieber Institute for Brain Development at Johns Hopkins Medical Campus
Inhaltsangabe
* 1. Neuroimaging genetics * Kristin L. Bigos, Ahmad R. Hariri, Daniel R. Weinberger * Imaging Genetics and Neurochemistry * 2.Molecular Neuroimaging Genetics * Patrick M. Fisher, Gitte Moos Knudsen * 3. Neuroreceptor Imaging of Genetic Variation Impacting the Serotonin Transporter * Greg Perlman, Christine DeLorenzo, J. John Mann, Ramin Parsey * 4. Imaging of Genetic Variation Impacting Dopamine Transmission Parameters * Elsmarieke van de Giessen, Rassil Ghazzaoui, Raj Narendran, Anissa Abi-Dargham * 5. Imaging Genetics of Dopamine Synaptic Terminal Activity * Giuseppe Blasi, Alessandro Bertolino * Imaging Genetics and Drug Discovery * 6. Variability of Antidepressant Drug Response: Contribution of Imaging Genetics studies * Ulrich Rabl, Bernhard M. Meyer, Lukas Pezawas * 7. Imaging Genetics of Pharmacological Response in Psychiatric Disorders * Philip R. Szeszko, Anil K. Malhotra * Imaging Genetics and Genetic Discovery * 8. Imaging Genetics of Williams Syndrome * Daniel P. Eisenberg, Ranjani Prabhakaran, Karen F. Berman * 9. Identifying Unanticipated Genes and Mechanisms in Serious Mental Illness: GWAS Based Imaging Genetics Strategies * Steven G. Potkin, Theo G. M. van Erp, Shichun Ling, Fabio Macciardi, Xiaohui Xie * 10. Imaging Genetics of Brain Structure * Jason L. Stein, Derrek P. Hibar, Paul M. Thompson * 11. Imaging Genetics of the Reward System * Caroline F. Zink * Imaging Genetics and Disease * 12. Imaging Genetics of Schizophrenia * Thomas M. Lancaster, Joanne L. Doherty, David E. Linden, Jeremy Hall * 13. Imaging Genetics of Depression * Matthew D. Sacchet, Lara C. Foland-Ross, Ian H. Gotlib * 14. Imaging Genetics of Anxiety Disorders * Mats Fredrikson * 15. Imaging Genetics of Bipolar Disorder * Martin Tesli, Ole A. Andreassen * 16. Genetic-neuroimaging Studies of Basal Ganglia Disorders * Trevor W. Robbins, James B. Rowe, Roger A. Barker * 17. Imaging Genetics of Antisocial Behavior and Psychopathy * Hayley M. Dorfman, Joshua W. Buckholtz * Imaging Genetics and the Environment * 18. Incorporating the Environment into Neurogenetics Research: An Imaging Gene by Environment Interactions (IG x E) Approach * Luke W. Hyde, Ryan Bogdan, Ahmad R. Hariri * Imaging Genetics and Cognition * 19. Imaging Genetics of Episodic Memory * Björn Rasch, Susanne Erk, Andreas Papassotiropoulos, Dominique J.-F. de Quervain * 20. Imaging Genetics of Working Memory * Tristram A. Lett, Eva J. Brandl, Daniel J. Müller, Andreas Heinz, Henrik Walter * Imaging Genetics of Advancing Age * 21. Neurobiology and Genetics of Cognitive Aging: Insights from Neuroimaging Studies * John C. Muse, Milap A. Nowrangi, Daniel R. Weinberger, Venkata S. Mattay * 22. Neuroimaging Genetics of Alzheimer's Disease * Theresa M. Harrison, Alison C. Burggren, Susan Y. Bookheimer * Imaging Genetics and Multi-Locus Models * 23. Imaging Genetics of the Hypothalamic Pituitary Adrenal Axis: Implications for Psychopathology * Nadia S. Corral-Frias, Lindsay J. Michalski, Christina R. Di Iorio, Ryan Bogdan * Index
* 1. Neuroimaging genetics * Kristin L. Bigos, Ahmad R. Hariri, Daniel R. Weinberger * Imaging Genetics and Neurochemistry * 2.Molecular Neuroimaging Genetics * Patrick M. Fisher, Gitte Moos Knudsen * 3. Neuroreceptor Imaging of Genetic Variation Impacting the Serotonin Transporter * Greg Perlman, Christine DeLorenzo, J. John Mann, Ramin Parsey * 4. Imaging of Genetic Variation Impacting Dopamine Transmission Parameters * Elsmarieke van de Giessen, Rassil Ghazzaoui, Raj Narendran, Anissa Abi-Dargham * 5. Imaging Genetics of Dopamine Synaptic Terminal Activity * Giuseppe Blasi, Alessandro Bertolino * Imaging Genetics and Drug Discovery * 6. Variability of Antidepressant Drug Response: Contribution of Imaging Genetics studies * Ulrich Rabl, Bernhard M. Meyer, Lukas Pezawas * 7. Imaging Genetics of Pharmacological Response in Psychiatric Disorders * Philip R. Szeszko, Anil K. Malhotra * Imaging Genetics and Genetic Discovery * 8. Imaging Genetics of Williams Syndrome * Daniel P. Eisenberg, Ranjani Prabhakaran, Karen F. Berman * 9. Identifying Unanticipated Genes and Mechanisms in Serious Mental Illness: GWAS Based Imaging Genetics Strategies * Steven G. Potkin, Theo G. M. van Erp, Shichun Ling, Fabio Macciardi, Xiaohui Xie * 10. Imaging Genetics of Brain Structure * Jason L. Stein, Derrek P. Hibar, Paul M. Thompson * 11. Imaging Genetics of the Reward System * Caroline F. Zink * Imaging Genetics and Disease * 12. Imaging Genetics of Schizophrenia * Thomas M. Lancaster, Joanne L. Doherty, David E. Linden, Jeremy Hall * 13. Imaging Genetics of Depression * Matthew D. Sacchet, Lara C. Foland-Ross, Ian H. Gotlib * 14. Imaging Genetics of Anxiety Disorders * Mats Fredrikson * 15. Imaging Genetics of Bipolar Disorder * Martin Tesli, Ole A. Andreassen * 16. Genetic-neuroimaging Studies of Basal Ganglia Disorders * Trevor W. Robbins, James B. Rowe, Roger A. Barker * 17. Imaging Genetics of Antisocial Behavior and Psychopathy * Hayley M. Dorfman, Joshua W. Buckholtz * Imaging Genetics and the Environment * 18. Incorporating the Environment into Neurogenetics Research: An Imaging Gene by Environment Interactions (IG x E) Approach * Luke W. Hyde, Ryan Bogdan, Ahmad R. Hariri * Imaging Genetics and Cognition * 19. Imaging Genetics of Episodic Memory * Björn Rasch, Susanne Erk, Andreas Papassotiropoulos, Dominique J.-F. de Quervain * 20. Imaging Genetics of Working Memory * Tristram A. Lett, Eva J. Brandl, Daniel J. Müller, Andreas Heinz, Henrik Walter * Imaging Genetics of Advancing Age * 21. Neurobiology and Genetics of Cognitive Aging: Insights from Neuroimaging Studies * John C. Muse, Milap A. Nowrangi, Daniel R. Weinberger, Venkata S. Mattay * 22. Neuroimaging Genetics of Alzheimer's Disease * Theresa M. Harrison, Alison C. Burggren, Susan Y. Bookheimer * Imaging Genetics and Multi-Locus Models * 23. Imaging Genetics of the Hypothalamic Pituitary Adrenal Axis: Implications for Psychopathology * Nadia S. Corral-Frias, Lindsay J. Michalski, Christina R. Di Iorio, Ryan Bogdan * Index
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