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neurology A fully updated and authoritative neurology resource The Queen Square Textbook has established itself as a favourite companion to clinical neurosciences training and teaching around the world, whilst retaining its role as an invaluable reference guide for physicians and other healthcare professionals working in neurology, general medicine and related specialties. The book continues to reflect the core values essential to the practice of clinical neurology in the 21st century. The third edition has been extensively revised and updated to take account of the rapid pace of progress in…mehr
neurology A fully updated and authoritative neurology resource The Queen Square Textbook has established itself as a favourite companion to clinical neurosciences training and teaching around the world, whilst retaining its role as an invaluable reference guide for physicians and other healthcare professionals working in neurology, general medicine and related specialties. The book continues to reflect the core values essential to the practice of clinical neurology in the 21st century. The third edition has been extensively revised and updated to take account of the rapid pace of progress in the neurosciences and patient care. Contemporary neurology has been changed by the COVID-19 pandemic, the climate emergency and the growing inequalities in healthcare resources. The new edition has been extensively revised to reflect these challenges and affords a greater emphasis on management and rehabilitation whilst continuing to reflect the coherence of a text produced from a single, closely-knit, centre of excellence. Highlights of the new edition include: * An updated approach to clinical examination, decision-making and diagnosis * New developments in neuroimmunology, pathology and genetics * Neuropalliative care * Ethical and legal issues in clinical neurology * The latest developments in the understanding and management of stroke, movement disorders, epilepsy, cognitive impairment, multiple sclerosis, infections, myelopathy, anterior horn cell disease, disorders of nerve and muscle, neuro-oncology, neurological disorders of hearing, balance and vision, and the neurological care of critical illness, sleep, neuropsychiatry, pain, autonomic and urological disorders. * An emphasis on treatment and rehabilitation of the person with a neurological disease The new edition marks a significant transition to reflect contemporary neurological practice during uncertain times. It mirrors the enormous changes in investigation, diagnosis and treatment that have occurred in recent years whilst maintaining the underlying principle that we do not treat diagnoses but, rather, we care for people affected by neurological disease.
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Autorenporträt
Robin Howard, PhD, FRCP, FFICM Dimitri Kullmann, FMedSci, FRS David Werring, PhD, FRCP, FESO Michael Zandi, PhD, FRCP
Inhaltsangabe
Contributors vii
About the Editors xiii
Foreword to the Third Edition xv
Preface to First Edition xvii
Preface to Second Edition xix
Preface to Third Edition xxi
Acknowledgements xxiii
1 Global Burden of Neurological Disease and the Neurology of Climate Change 1 Hadi Manji and Sanjay Sisodiya
2 Approach to the Patient with Neurological Disease 17 Robin Howard, Gerry Christofi, Alex Rossor, Jason Warren and David Werring
3 Decision Making, Ethics and Law in Neurology 37 Jonathan Martin and Alex Ruck Keene
4 Neuropathology: Introduction to History, Diagnostic Approaches, Techniques and their Interpretation 53 Sebastian Brandner
5 Neuroimaging 67 Frederik Barkhof and Francesco Carletti
6 Neurogenetics 79 Henry Houlden, Andrea Cortese and Edward J. Wild
7 Neuroimmunology 91 Michael Zandi, Aisling Carr, Rachel Brown and Michael Lunn
8 Stroke and Cerebrovascular Diseases 107 David Werring, Matthew Adams, Laura Benjamin, Martin Brown, Arvind Chandratheva, Peter Cowley, Joan Grieve, Fiona Humphries, Hans Rolf Jäger, Nicholas Losseff, Richard Perry, Robert Simister and Ahmed Toma
9 Movement Disorders 199 Thomas Foltynie, Kailash Bhatia, Carla Cordivari, Eileen Joyce, Prasad Korlipara, Patricia Limousin, Tabish A. Saifee, Sarah Tabrizi and Thomas Warner
10 Epilepsy and Related Disorders 247 John Duncan, Josemir Sander, Ali Alim-Marvasti, Simona Balestrini, Sallie Baxendale, Dorothea Bindman, Krishna Chinthapalli, Fahmida Chowdhury, Beate Diehl, Sofia Eriksson, Jackie Foong, Dominic Heaney, Sofia Khan, Matthias Koepp, Dimitri Kullmann, Sanjeev Rajakulendran, Fergus Rugg-Gunn, Meneka Sidhu, Sanjay Sisodiya, Jane de Tisi, Maria Thom, Matthew Walker and Mahinda Yogarajah
11 Cognitive Impairment and Dementia 319 Jason Warren, John Collinge, Nick Fox, Simon Mead, Catherine Mummery, Jonathan Rohrer, Martin Rossor, Jonathan Schott and Rimona Weil
12 Infection in the Nervous System 369 Robin Howard, Laura Benjamin, Sophia De-Saram, Catherine Houlihan and Hadi Manji
13 Cranial Nerve Disorders 433 Robin Howard, Jeremy Chataway and Paul Jarman
14 Spinal Column and Spinal Cord Disorders 463 Tabish A. Saifee, Simon Farmer, Sachit Shah and David Choi
15 Disorders of the Motor Cells: The Motor Neuron Diseases 499 Andrea Malaspina, Jan Clarke, Pietro Fratta, Robin Howard, Ross Nortley, Richard Orrell, Rickie Patani, Katie Sidle and Michaela Waltho
16 Diseases of the Peripheral Nerves 517 Michael Lunn, Alex Rossor and Mary Reilly
17 Disorders of the Neuromuscular Junction 561 Jennifer Spillane, Robin Howard, Dimitri Kullmann and Georgiana Logou
18 Disorders of Muscle 575 Jasper Morrow, Michael Hanna, Matt Parton and Christopher Turner
19 Multiple Sclerosis and Demyelinating Diseases 603 Siobhan Leary, Wallace Brownlee, Noreen Barker, Declan Chard, Jeremy Chataway, Karen Chung, Olga Ciccarelli, Gavin Giovannoni, Nevin John, Zhaleh Khaleeli, Josephine Swanton, Ahmed Toosy, Anand Trip, Heather Wilson and Alan Thompson
20 Neuro-Oncology 655 Jeremy Rees, Sebastian Brandner, Naomi Fersht, Joan Grieve, Gary Hotton, Michael Kosmin, Vittorio Russo, Lewis Thorne and Steffi Thust
21 Headache 721 Manjit Matharu, Paul Shanahan, Tim Young and Salwa Kamourieh
22 Neuro-Ophthalmology 741 James Acheson, Fion Bremner, Sara Ajina, Gordon Plant, Robin Howard, Alexander Leff and Ahmed Toosy
23 Neuro-Otology: Dizziness, Balance and Hearing 797 Diego Kaski, Doris-Eva Bamiou, Adolfo Bronstein and Nehzat Koohi
24 Cerebellar Ataxias and Related Conditions 839 Nicholas Wood
1 Global Burden of Neurological Disease and the Neurology of Climate Change 1 Hadi Manji and Sanjay Sisodiya
2 Approach to the Patient with Neurological Disease 17 Robin Howard, Gerry Christofi, Alex Rossor, Jason Warren and David Werring
3 Decision Making, Ethics and Law in Neurology 37 Jonathan Martin and Alex Ruck Keene
4 Neuropathology: Introduction to History, Diagnostic Approaches, Techniques and their Interpretation 53 Sebastian Brandner
5 Neuroimaging 67 Frederik Barkhof and Francesco Carletti
6 Neurogenetics 79 Henry Houlden, Andrea Cortese and Edward J. Wild
7 Neuroimmunology 91 Michael Zandi, Aisling Carr, Rachel Brown and Michael Lunn
8 Stroke and Cerebrovascular Diseases 107 David Werring, Matthew Adams, Laura Benjamin, Martin Brown, Arvind Chandratheva, Peter Cowley, Joan Grieve, Fiona Humphries, Hans Rolf Jäger, Nicholas Losseff, Richard Perry, Robert Simister and Ahmed Toma
9 Movement Disorders 199 Thomas Foltynie, Kailash Bhatia, Carla Cordivari, Eileen Joyce, Prasad Korlipara, Patricia Limousin, Tabish A. Saifee, Sarah Tabrizi and Thomas Warner
10 Epilepsy and Related Disorders 247 John Duncan, Josemir Sander, Ali Alim-Marvasti, Simona Balestrini, Sallie Baxendale, Dorothea Bindman, Krishna Chinthapalli, Fahmida Chowdhury, Beate Diehl, Sofia Eriksson, Jackie Foong, Dominic Heaney, Sofia Khan, Matthias Koepp, Dimitri Kullmann, Sanjeev Rajakulendran, Fergus Rugg-Gunn, Meneka Sidhu, Sanjay Sisodiya, Jane de Tisi, Maria Thom, Matthew Walker and Mahinda Yogarajah
11 Cognitive Impairment and Dementia 319 Jason Warren, John Collinge, Nick Fox, Simon Mead, Catherine Mummery, Jonathan Rohrer, Martin Rossor, Jonathan Schott and Rimona Weil
12 Infection in the Nervous System 369 Robin Howard, Laura Benjamin, Sophia De-Saram, Catherine Houlihan and Hadi Manji
13 Cranial Nerve Disorders 433 Robin Howard, Jeremy Chataway and Paul Jarman
14 Spinal Column and Spinal Cord Disorders 463 Tabish A. Saifee, Simon Farmer, Sachit Shah and David Choi
15 Disorders of the Motor Cells: The Motor Neuron Diseases 499 Andrea Malaspina, Jan Clarke, Pietro Fratta, Robin Howard, Ross Nortley, Richard Orrell, Rickie Patani, Katie Sidle and Michaela Waltho
16 Diseases of the Peripheral Nerves 517 Michael Lunn, Alex Rossor and Mary Reilly
17 Disorders of the Neuromuscular Junction 561 Jennifer Spillane, Robin Howard, Dimitri Kullmann and Georgiana Logou
18 Disorders of Muscle 575 Jasper Morrow, Michael Hanna, Matt Parton and Christopher Turner
19 Multiple Sclerosis and Demyelinating Diseases 603 Siobhan Leary, Wallace Brownlee, Noreen Barker, Declan Chard, Jeremy Chataway, Karen Chung, Olga Ciccarelli, Gavin Giovannoni, Nevin John, Zhaleh Khaleeli, Josephine Swanton, Ahmed Toosy, Anand Trip, Heather Wilson and Alan Thompson
20 Neuro-Oncology 655 Jeremy Rees, Sebastian Brandner, Naomi Fersht, Joan Grieve, Gary Hotton, Michael Kosmin, Vittorio Russo, Lewis Thorne and Steffi Thust
21 Headache 721 Manjit Matharu, Paul Shanahan, Tim Young and Salwa Kamourieh
22 Neuro-Ophthalmology 741 James Acheson, Fion Bremner, Sara Ajina, Gordon Plant, Robin Howard, Alexander Leff and Ahmed Toosy
23 Neuro-Otology: Dizziness, Balance and Hearing 797 Diego Kaski, Doris-Eva Bamiou, Adolfo Bronstein and Nehzat Koohi
24 Cerebellar Ataxias and Related Conditions 839 Nicholas Wood
25 Restorative Neurology, Rehabilitation a
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