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Neuropathic pain is one of the most common, most debilitating, most costly, and most difficult to treat categories of chronic pain conditions that are characterized by a lesion or disease of the somatosensory nervous system. Managing neuropathic pain is challenging and requires skillful assessment and comprehensive and integrated treatment strategies that are mechanism-guided, evidence-based, and individualized. However, these critical and integral elements are very fragmented in the current literature. The mechanistic understanding of neuropathic pain is typically found in basic research…mehr
Neuropathic pain is one of the most common, most debilitating, most costly, and most difficult to treat categories of chronic pain conditions that are characterized by a lesion or disease of the somatosensory nervous system. Managing neuropathic pain is challenging and requires skillful assessment and comprehensive and integrated treatment strategies that are mechanism-guided, evidence-based, and individualized. However, these critical and integral elements are very fragmented in the current literature. The mechanistic understanding of neuropathic pain is typically found in basic research articles. Clinical research evidence is presented in forms of clinical trials with emphasis on minimizing biases such as those from patient selection and assessment. Individualized considerations for each patient are usually presented in case reports and problem-based learning discussions. This book overcomes these barriers and integrates all the critical elements around individual patient care into a coherent management strategy that is practical and applicable to daily clinical practice. Rather than compiling what have been published in the literature, this work emphasizes on identifying and highlighting the key points or findings that guide decision-making in clinical practice. It integrates the key points around a typical case scenario that not only represents the core of the diagnostic and therapeutic processes but also allows introduction and differentiation of painful conditions that bare similarities with the case in hand. The overarching goal is to improve clinical outcomes through better understanding of the mechanisms, more accurate diagnosis, and wiser and more comprehensive treatment strategies.
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Jianguo Cheng, MD, PhD, is Professor of Anesthesiology and Director of the Cleveland Clinic Multidisciplinary Pain Medicine Fellowship Program. Dr. Cheng is the President of American Academy of Pain Medicine (AAPM) and immediate past Chair of the US Section of World Institute of Pain. He has recently been appointed to the US Department of Health and Human Services (HHS) Pain Management Best Practices Inter-agency Task Force (PMTF). Dr. Cheng is also a member of the Centers for Medicare & Medicaid Services (CMS) Expert Work Group (EWG). As a clinician, Dr. Cheng was recognized by Best Doctors in America (Best Doctors Inc.), 70 Best Pain Management Physicians in the US (Becker's ASC Review), and Top Doctors (International Association of Anesthesiologists). He has published more than 250 articles including investigations on opioid tolerance and neuropathic pain and a textbook "Fundamentals of Pain Medicine" (Springer-Nature). In addition, Dr. Cheng plays active leadership roles in the Association of University Anesthesiologists (AUA), American Board of Anesthesiology (ABA), American Society of Anesthesiologists (ASA), and American Academy of Regenerative Medicine. He also serves as Senior Editor, Associate Editor, and Section Editor for the scientific journals of Pain Medicine, Pain Practice, and Pain Physician.
Inhaltsangabe
* Part I: Overview of Neuropathic Pain * 1. Concept and Overview of Neuropathic Pain * Jianguo Cheng * 2. Classification of Neuropathic Pain * Abdullah Kandil and Danielle Perret * 3. Mechanisms of Neuropathic Pain * Jianguo Cheng * 4. Assessment and Diagnosis of Neuropathic Pain * Erik C. Hustak * 5. Nonpharmacological Treatment of Neuropathic Pain * Ravi Mirpuri and Danielle Perret * 6. Pharmacological Treatment of Neuropathic Pain * Randall Brewer, Rinoo Shah, and Elizabeth Casserly * 7. Interventional Treatment of Neuropathic Pain * Jiang Wu and Jianguo Cheng * 8. Surgical Treatment of Neuropathic Pain * Jianguo Cheng and Wenbao Wang * 9. Post-Surgical Neuralgia * John P. Kenny IV and Dalia Elmofty * 10. Post-Tramatic Neuralgia * Magdalena Anitescu, Joshua Frenkel, and Bradley A. Silva * Part II: Focal or Multifocal Lesions of the Peripheral Nervous System * 11. Herpes Zoster and Postherpetic Neuralgia * Jianguo Cheng * 12. Entrapment Syndromes * Jonathan P. Eskander, Zeeshan Malik, and Rinoo V. Shah * 13. Neurotrauma * John Blackburn and Alexander Bautista * 14. Stump Pain * Jagan Devarajan and Beth Minzter * 15. Ischemic Neuropathy * Jagan Devarajan and Beth Minzter * Part III: Focal or Multifocal Lesions of the Peripheral Nervous System * 16. Diabetic Peripheral Neuropathy * Maximilian Hsia-Kiung * 17. HIV Polyneuropathy * Hersimren Basi * 18. Immune Related Neuropathy * Whit Braddy * 19. Metabolic, Endocrine, and Other Toxic Neuropathies * Martin J. Carney, Preya K. Jhita, Harold J. Campbell, Michelle St. Robin, Mark Motejunas, and Alan D. Kaye * Part IV: Lesions of the CNS * 20. Spinal Cord Injury * Justin F. Averna, Alexander Bautista, George C. Chang Cien, and Michael Saulino * 21. Brain Infarction (thalamus and brainstem) * Theodore G. Eckman and Jianguo Cheng * 22. Spinal Cord Infarction * Randall P. Brewer, Sai Munampalli, and Aliza Kumpinsky * 23. Syringomyella * Ashwin Varma, Timothy Bednar, and Gulshan Doulatram * 24. Multiple Sclerosis * Samuel W. Samuel and Jianguo Cheng * 25. Phantom Pain * Jagan Devarajan and Beth Minzter * 26. Cervical Radiculopathy * Samuel W. Samuel and Eduardo E. Icaza * Part V: Spinal Nerve Root Disease: Radicular Pain * 27. Thoracic Radicular Pain * Victor Foorsov and Sarah Pastoriza * 28. Lumbar Radicular Pain * Varun Rimmalapudi and Radhika Grandhe * 29. Arachnoiditis * Zeehsan Malik, Shilpadevi Patil, Sailesh Arulkumar, and Rinoo Shah * 30. Trigeminal Neuralgia * Radhika Grandhe, Eli Johnson Harris, and Eugene Koshkin * 31. Glossopharyngeal Neuralgia * George C. Chang Chien, Andrea M. Trescot, and Agnes R. Stogicza * Part VI: Neuropathic Pain of the Head and Neck * 32. Persistent Idiopathic Facial Pain * Trevor Van Oostrom * 33. Occipital Neuralgia * Amin Deroee and Jianguo Cheng * 34. Complex Regional Pain Syndrome * Brian A. Kim and Timothy Furnish
* Part I: Overview of Neuropathic Pain * 1. Concept and Overview of Neuropathic Pain * Jianguo Cheng * 2. Classification of Neuropathic Pain * Abdullah Kandil and Danielle Perret * 3. Mechanisms of Neuropathic Pain * Jianguo Cheng * 4. Assessment and Diagnosis of Neuropathic Pain * Erik C. Hustak * 5. Nonpharmacological Treatment of Neuropathic Pain * Ravi Mirpuri and Danielle Perret * 6. Pharmacological Treatment of Neuropathic Pain * Randall Brewer, Rinoo Shah, and Elizabeth Casserly * 7. Interventional Treatment of Neuropathic Pain * Jiang Wu and Jianguo Cheng * 8. Surgical Treatment of Neuropathic Pain * Jianguo Cheng and Wenbao Wang * 9. Post-Surgical Neuralgia * John P. Kenny IV and Dalia Elmofty * 10. Post-Tramatic Neuralgia * Magdalena Anitescu, Joshua Frenkel, and Bradley A. Silva * Part II: Focal or Multifocal Lesions of the Peripheral Nervous System * 11. Herpes Zoster and Postherpetic Neuralgia * Jianguo Cheng * 12. Entrapment Syndromes * Jonathan P. Eskander, Zeeshan Malik, and Rinoo V. Shah * 13. Neurotrauma * John Blackburn and Alexander Bautista * 14. Stump Pain * Jagan Devarajan and Beth Minzter * 15. Ischemic Neuropathy * Jagan Devarajan and Beth Minzter * Part III: Focal or Multifocal Lesions of the Peripheral Nervous System * 16. Diabetic Peripheral Neuropathy * Maximilian Hsia-Kiung * 17. HIV Polyneuropathy * Hersimren Basi * 18. Immune Related Neuropathy * Whit Braddy * 19. Metabolic, Endocrine, and Other Toxic Neuropathies * Martin J. Carney, Preya K. Jhita, Harold J. Campbell, Michelle St. Robin, Mark Motejunas, and Alan D. Kaye * Part IV: Lesions of the CNS * 20. Spinal Cord Injury * Justin F. Averna, Alexander Bautista, George C. Chang Cien, and Michael Saulino * 21. Brain Infarction (thalamus and brainstem) * Theodore G. Eckman and Jianguo Cheng * 22. Spinal Cord Infarction * Randall P. Brewer, Sai Munampalli, and Aliza Kumpinsky * 23. Syringomyella * Ashwin Varma, Timothy Bednar, and Gulshan Doulatram * 24. Multiple Sclerosis * Samuel W. Samuel and Jianguo Cheng * 25. Phantom Pain * Jagan Devarajan and Beth Minzter * 26. Cervical Radiculopathy * Samuel W. Samuel and Eduardo E. Icaza * Part V: Spinal Nerve Root Disease: Radicular Pain * 27. Thoracic Radicular Pain * Victor Foorsov and Sarah Pastoriza * 28. Lumbar Radicular Pain * Varun Rimmalapudi and Radhika Grandhe * 29. Arachnoiditis * Zeehsan Malik, Shilpadevi Patil, Sailesh Arulkumar, and Rinoo Shah * 30. Trigeminal Neuralgia * Radhika Grandhe, Eli Johnson Harris, and Eugene Koshkin * 31. Glossopharyngeal Neuralgia * George C. Chang Chien, Andrea M. Trescot, and Agnes R. Stogicza * Part VI: Neuropathic Pain of the Head and Neck * 32. Persistent Idiopathic Facial Pain * Trevor Van Oostrom * 33. Occipital Neuralgia * Amin Deroee and Jianguo Cheng * 34. Complex Regional Pain Syndrome * Brian A. Kim and Timothy Furnish
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