Stroke is the third major cause of death in the western world, and recent data provide hope that treatments may soon be available. Written by world experts on the mechanisms involved in neurodegeneration, Neuroprotective Agents and Cerebral Ischaemia presents an up-to-date review of current research and developing therapies. This book is essential reading for all clinicians and researchers searching for neuroprotective drugs.
- Describes the mechanisms involved in cell death and the biochemical changes occurring during an ischaemic episode
- Presents the different factors affecting the neurodegenerative process and how compounds acting on these systems may lead to novel neuroprotective agents
- Reviews in vitro and in vivo models of stroke and the activity of putative neuroprotective drugs
- Discusses the application of preclinical data to formulate approaches to a clinical problem
- Provides detailed reviews of both completed clinical trials and those currently underway
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