New Concepts of Antiviral Therapy (eBook, PDF)

Redaktion: Bogner, Elke; Holzenburg, Andreas

• Format: PDF

Produktbeschreibung

Antiviral drugs are vital - but imperfect - tools for treatment and prevention of viral infections. Undesirable effects, from drug resistant viruses to low oral bioavailability, toxicity and severe side effects limit clinical usefulness. These factors drive demand for improved antiviral strategies. This book offers an up-to-date review of new drugs and targets, novel modes of action, vector-based treatments and even the blocking of defined genes by inhibiting mRNA formation (siRNA). Includes contributions by acknowledged experts; the book will serve as a compendium for R&D and educational professionals, and be of value for students.

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Produktdetails

• Verlag: Springer US
• Seitenzahl: 538
• Erscheinungstermin: 31. Januar 2007
• Englisch
• ISBN-13: 9780387310473
• Artikelnr.: 43731117

Inhaltsangabe

Concepts of therapy for RNA viruses.- Therapeutic vaccination in chronic hepadnavirus infection.- Characterization of targets for antiviral therapy of Flaviviridae infections.- Inhibition of Hepatitis C virus by nucleic acid-based antiviral approaches.- Inhibitors of respiratory viruses.- Anti-viral approaches against influenza viruses.- A new approach to an Influenza virus live vaccine: Modification of eleavage site of the haemagglu reverse genetics.- New concepts in anti-HIV therapies.- Evaluation of current strategies to inhibit HIV entry, integration and maturation.- Managing antiretroviral resistance.- Concepts of therapy for DNA viruses.- Selective inhibitors of the replication of poxviruses.- Maribavir: A promising new antiherpes therapeutic agent.- Benzimidazole-D-ribonucleosides as antiviral agents that target HCMV terminase.- Recent developments in anti-herpesviral therapy based on protein kinase inhibitors.- Immune therapy against papillomavirus-related tumors in humans.- Concepts of therapy for emerging viruses.- The SARS Coronavirus receptor ACE 2 A potential target for antiviral therapy.- Therapy of Ebola and Marburg virus infections.- General concepts of therapy.- Proteasome inhibitors as complementary or alternative antiviral therapeutics.- Human monoclonal antibodies for prophylaxis and therapy of viral infections.- Vector-based antiviral therapy.