Owen P. Green, Guy Healing

Non-Clinical Vascular Infusion Technology, Volume I (eBook, PDF)

The Science

• Format: PDF

Produktbeschreibung

With the evolution of vascular infusion technology, its use in the preclinical safety assessment of pharmaceuticals has become increasingly widespread. Hence, a need has developed for a single source on the scientific principles behind this technology. This book brings together current knowledge and underlying practices from around the world to help refine the procedures and enhance the understanding of infusion technology. It addresses the physical and physiological aspects including body fluid dynamics, physico-chemical factors, vascular infusion dynamics, formulation-specific considerations, and equipment compatibility.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 215
• Erscheinungstermin: 26. September 2013
• Englisch
• ISBN-13: 9781439874509
• Artikelnr.: 40066975

Autorenporträt

Owen Green is a toxicologist who has spent nearly 40 years in the preclinical toxicology industry within leading global CROs or as an independent consultant in toxicology to pharmaceutical and chemical sectors. Following his masters degree in pharmacological biochemistry and Ph.D. studying chronic renal disease, he has spent many years working with and studying the practice of infusion technology in non-clinical toxicology programmes. He is one of the founders and current chairman of the Infusion Technology Organisation. This is an international group set up to share commercial and academic experiences with the technology in order to improve the techniques and scientific understanding for the benefit of the animal models involved and to improve the scientific quality of the data generated.

Guy Healing is an experienced regulatory toxicologist who has worked in pre-clinical pharmaceutical R&D for nearly 20 years, and prior to that in agrochemical R&D and for a global CRO. He obtained a BSc in biochemistry at Cardiff University and his Ph.D. investigating the role of iron and oxygen-derived free radicals in the pathogenesis of renal ischaemic damage while working for the Medical Research Council. Guy is a Fellow of the British Toxicology Society and has been editor of its newsletter as well as a member of the Executive Committee. He has published previously in the area of infusion technology, including the Handbook of Pre-clinical Continuous Intravenous Infusion in 2000.