Prakash Sambhara

Nucleic Acid Sensors and Antiviral Immunity (eBook, PDF)

• Format: PDF

Produktbeschreibung

The discovery of Toll-like receptors (TLRs) in the late 1990s ushered in a new age of discovery for innate immunity. The importance of TLRs for immunology and biomedical research was recognized with the Nobel Prize for Medicine or Physiology in 2011. The prize was shared by three scientists: Ralph Steinman (for the discovery of dendritic cells, whi

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 284
• Erscheinungstermin: 26. November 2012
• Englisch
• ISBN-13: 9781498713658
• Artikelnr.: 57102078

Autorenporträt

Dr. Prakash Sambhara

Inhaltsangabe

1. Antiviral Responses in Invertebrates 2. Overview of TLRs 3. Nucleic
Acid-Sensing TLR Signaling Pathways 4. Alternative Regulatory Mechanisms of
TLR Signaling 5. Intracellular Viral RNA Sensors: RIG-I Like Receptors 6.
Contribution of LGP2 to Viral Recognition Pathways 7. The Mitochondrial
Immune Signaling Complex 8. DNA Sensors and Anti-Viral Immune Responses 9.
Mechanisms of Interferon Antagonism by Poxviruses 10. Innate Immune Evasion
Strategies of HCV and HIV: Common Themes for Chronic Viral Infection 11.
Innate Immune Evasion Strategies of Influenza A Virus 12. Autophagy in
Antiviral Immunity 13. Synthetic and Natural Ligands of RLR 14. Antiviral
Actions of Double-Stranded RNA 15. Ligands of Pathogen Sensors as Antiviral
Agents