Nutraceuticals (eBook, ePUB)

Efficacy, Safety and Toxicity
Redaktion: Gupta, Ramesh C; Srivastava, Ajay; Lall, Rajiv

• Format: ePub

Produktbeschreibung

Nutraceuticals: Efficacy, Safety and Toxicity, Second Edition, brings together everything that is currently known about nutraceuticals and their potential toxic effects. The book introduces readers to nutraceuticals, herbal medicines, Ayurvedic medicines, prebiotics, probiotics, adaptogens, and their uses and specific applications. This essential reference discusses the mechanism of action for the judicious use of these nutraceuticals and the best tools for their evaluation before detailing the safety and toxicity of nutraceuticals and interactions with other therapeutic drugs. Finally, and crucially, regulatory aspects from around the world are covered.

Completely revised and updated, this updated edition provides toxicologists, pharmacologists, pharmaceutical scientists, and those interested in medicinal plants and natural products with a comprehensive overview of the most effective tools upon which to evaluate the safety and toxicity of nutraceuticals, prebiotics, probiotics and alternative medicines.

• Presents a completely revised and updated resource on the impact of nutraceuticals and various disease states such as diabetes and ophthalmic and dermal diseases
• Grants an overview of the current state-of-the-science of nutraceuticals, their use and applications, and known adverse effects
• Provides effective tools to evaluate the potential toxicity of any nutraceutical
• Includes details of regulatory issues as written by international experts

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 1396
• Erscheinungstermin: 27. Januar 2021
• Englisch
• ISBN-13: 9780128212462
• Artikelnr.: 61687886

Inhaltsangabe

Section I. Applications of nutraceuticals in common diseases and disorders
1. Nutraceuticals in central nervous system diseases: potential mechanisms
of neuroprotection 2. Prevention of neurodegenerative disorders by
nutraceuticals 3. Cognitive effects of nutraceuticals 4. Nutraceuticals in
anxiety and stress 5. Countering cardiovascular diseases with
nutraceuticals 6. Nutraceuticals for diabetes and glucose balance 7. Role
of nutraceuticals in respiratory and allied diseases 8. Nutraceuticals in
hepatic diseases 9. Nutraceuticals in renal diseases 10. Nutraceuticals in
gastrointestinal disorders 11. Nutraceuticals in reproductive and
developmental disorders 12. Nutraceuticals in ophthalmic diseases 13.
Nutraceuticals in dermal diseases 14. Nutraceuticals in arthritis 15.
Nutraceuticals in sports activities and fatigue 16. Role of nutraceuticals
as adaptogens 17. Nutraceuticals for weight loss 18. Nutraceuticals in
cancer prevention 19. Application of "nano? nutraceuticals in medicine
Section II. Models and mechanisms in evaluation of nutraceuticals 20. The
biology of nutrients: genetic and molecular principles 21. Genomic and
proteomic mechanisms and models in toxicity and safety evaluation of
nutraceuticals 22. Transcriptomic profiling for safety and toxicity
evaluation of nutraceuticals 23. Target identification and polypharmacology
of nutraceuticals 24. Systems pharmacology investigation of mechanism of
action of nutraceuticals 25. Noninvasive in vivo optical imaging models for
safety and toxicity testing 26. Flow cytometry and light-scattering
techniques in evaluation of nutraceuticals 27. Zebrafish as a model system
to evaluate the safety and toxicity of nutraceuticals 28. Caenorhabditis
elegans: an elegant model organism for evaluating the neuroprotective and
neurotherapeutic potential of nutraceuticals 29. Alternative in vitro
models for safety and toxicity evaluation of nutraceuticals 30.
Mitochondria as a target for safety and toxicity evaluation of
nutraceuticals 31. Oxidative stress and excitotoxicity: antioxidants from
nutraceuticals Section III. Common nutraceuticals 32. Caffeine: an
evaluation of the safety database 33. Biological activities and potential
nanotechnological delivery of resveratrol 34. Melatonin: a safe
nutraceutical and clinical agent 35. Standardized turmeric and curcumin 36.
Curcuminoid-metal complexes for oxidative stress 37. Fenugreek: multiple
health benefits 38. Cannabis sativa: an overview 39. Cannabidiol safety 40.
St John's wort (Hypericum perforatum L) 41. Green tea 42. Green coffee
beans 43. Quercetin 44. German chamomile 45. Isoflavones: toxicological
aspects and efficacy  46. Propolis 47. Bee products as nutraceuticals to
nutraceuticals for bees 48. Ginkgo biloba 49. Chinese ginseng 50.
Ashwagandha: multiple health benefits 51. Astaxanthin: health benefits and
toxicity 52. Thymoquinone 53. Glucosinolates 54. Organosulfur compounds as
nutraceuticals 55. Arginine and citrulline as nutraceuticals: efficacy and
safety in diseases 56. Neem Extract 57. Spirulina 58. Garcinia cambogia 59.
Vitamin E TPGS and its applications in nutraceuticals 60. Role of
transferrin: an iron-binding protein in health and diseases 61. Glutamine
supplementation: hope, hype, or stay tuned? 62. What to do with placenta
after birth: is it a waste? 63. Chitin, chitosan, and their derivatives
Section IV. Prebiotics and probiotics 64. Prebiotics: safety and toxicity
considerations 65. Probiotics: safety and toxicity considerations 66.
Synbiotics: safety and toxicity considerations Section V. Nutraceuticals in
veterinary medicine 67. Nutraceuticals in animal health and diseases
Section VI. Toxicity and toxic interactions 68. Toxic contamination of
nutraceuticals and food ingredients 69. Nutraceuticals and adverse outcome
pathways 70. Interactions between nutraceuticals/nutrients and nutrients
and therapeutic drugs 71. Genotoxicity evaluation of nutraceuticals
Section VII. Regulatory aspects 72. The regulatory framework for
nutraceuticals: North America 73. Evaluation and regulation of food
supplements: European perspective 74. Regulatory guidelines for
nutraceuticals in India: an overview 75. Regulatory aspects of
nutraceuticals: Chinese perspective 76. Uses and regulation of
nutraceuticals: Australia and New Zealand 77. Regulatory aspects of
nutraceuticals: Japanese perspective 78. Nutraceuticals: the Turkish
perspective