Nutritional Epigenomics (eBook, ePUB)

• Format: ePub

Produktbeschreibung

Nutritional Epigenomics offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition's role in the epigenomic regulation of disease, health and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet's role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development, among other processes. Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration, among other disorders.

Diet-gut microbiome interactions in the epigenomic regulation of disease are also discussed, as is the role of micronutrients and milk miRNAs in epigenetic regulation. Finally, chapter authors examine ongoing discussions of race and ethnicity in the social-epigenomic regulation of health and disease.

• Empowers the reader to employ nutritional epigenomics approaches in their own research
• Discusses the latest topics in nutritional epigenomics in the regulation of aging, circadian rhythm, inheritance and fetal development, as well as metabolism and disease
• Offers a full grounding in epigenetic reprogramming and nutritional intervention in the treatment and prevention of disease, as informed by population-based studies

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 478
• Erscheinungstermin: 20. Juli 2019
• Englisch
• ISBN-13: 9780128173107
• Artikelnr.: 61688923

Inhaltsangabe

SECTION I Introduction 1. Introduction to nutritional epigenomics
SECTION II Epigenetic regulators 2. DNA methylation and chromatin
modifications 3. Small non-coding RNAs as epigenetic regulators
SECTION III Epigenomic regulation of disease 4. The impact of race and
ethnicity in the social epigenomic regulation of disease 5. The epigenomic
impact of methylation in metabolic dysfunction and cancer 6. The role for
DNA/RNA methylation on neurocognitive dysfunctions 7. Histone acylation in
the epigenomic regulation of insulin action and metabolic disease 8. Cancer
and non-coding RNAs 9. Race in the social-epigenomic regulation of pre- and
perinatal development 10. Maternal nutrition, epigenetic programming and
metabolic syndrome 11. Epigenetic inheritance of metabolic signals 12. The
paternal diet regulates the offspring epigenome and health
SECTION V Nutritional epigenomics and the circadian clock 13. The interplay
between diet, epigenetics and the circadian clock 14. Epigenetic regulation
of the fetal circadian clock: implications for nutritional programming of
circadian and metabolic function 15. The role for the microbiome in the
regulation of the circadian clock and metabolism
SECTION VI Carloric restriction and exercise in the epigenomic regulation
of aging and disease 16. Epigenomic reprogramming of caloric restriction on
aging 17. Dietary restriction in the epigenomic regulation of
cardiovascular diseases 18. Epigenomic adaptations of exercise in the
control of metabolic disease and cancer
SECTION VII Macro- and micronutrients as epigenomic regulators of health
and disease 19. B-vitamins and one-carbon metabolism: impacts on the
epigenome during development 20. Food bioactives in the epigenomic
regulation of metabolic disease 21. Stilbenoids as dietary regulators of
the cancer epigenome 22. Regulation of non-coding RNAs by phytochemicals
for cancer therapy 23. Short chain fatty acids as epigenetic and metabolic
regulators of neurocognitive health and disease
SECTION VIII Diet, epigenetics and the microbiome 24. Diet-microbiome
interactions and the regulation of the epigenome 25. Gut dysbiosis and its
epigenomic impact on disease 26. Microbiota, the brain and epigenetics