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Obsessive-compulsive disorder affects approximately one person in 40 and causes great suffering. Effective treatments are available that can help many, and our understanding of the psychology, neurobiology, and clinical treatment of the disorder has advanced dramatically over the past 25 years. Nevertheless, much remains to be learned, and a substantial minority of patients benefit little even from the best treatments we have to offer today. This volume provides the first comprehensive summary of the state of the field, summarizing topics ranging from genetics and neurobiology through…mehr
Obsessive-compulsive disorder affects approximately one person in 40 and causes great suffering. Effective treatments are available that can help many, and our understanding of the psychology, neurobiology, and clinical treatment of the disorder has advanced dramatically over the past 25 years. Nevertheless, much remains to be learned, and a substantial minority of patients benefit little even from the best treatments we have to offer today. This volume provides the first comprehensive summary of the state of the field, summarizing topics ranging from genetics and neurobiology through cognitive psychology, clinical treatment, related conditions, societal implications, and personal experiences of patients and clinicians. This book is unique in its comprehensive coverage that extends far beyond the realm of cognitive-behavioral therapy. As such it will serve as a valuable introduction to those new to the field, a fascinating resource for OCD suffers and their families, and an essential reference for students, clinicians, and researchers.
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Autorenporträt
Christopher Pittenger is Director of the Yale OCD Research Clinic and Associate Professor of Psychiatry at Yale University. He trained at Columbia University, where he both received his medical degree and completed his Ph.D. with Nobel Prize winner Eric Kandel. He then completed his clinical training in psychiatry at Yale, where he joined the faculty in 2007. Dr. Pittenger lives outside New Haven, CT, with his wife, four children, three cats, and six chickens.
Inhaltsangabe
* 1. Introduction: Narratives of OCD - Elias Aboujaoude and Christopher Pittenger * Section 1: Clinical Presentation and Diagnosis * 2. Clinical Presentation of OCD - Fred Penzel * 3. Pediatric OCD: Clinical Course, Phenomology, and Assessment - Rachel E. Ginsberg, Samantha Morrison, and Anthony Puliafico * 4. Epidemiology, Comorbidity, and Burden of OCD - Albina R. Torres, Leonardo F. Fontenelle, Roseli G. Shavitt, Marcelo Q. Hoexter, Christopher Pittenger, and Euripedes C. Miguel * 5. Natural History and Long-Term Outcome of OCD - Michael H. Bloch * 6. Quality of Life and Psychosocial Functioning in OCD - Christina L. Boisseau, Carly M. Schwartzman, and Steven A. Rasmussen * 7. Psychodynamic perspectives on OCD - Robert A. King * Section 2: Phenomenology and Cognitive Psychology * 8. Symptom heterogeneity in OCD: A dimensional approach - Maria Concei Conceição do Rosário, Marcelo Batistutto, and Ygor Ferrao * 9. Incompleteness and harm avoidance - Stefano Pallanti, Jennifer Barnes, Christopher Pittenger, and Jane Eisen * 10. Disgust and OCD - Lauren Mancusi and Dean McKay * 11. Sensory Processing and Intolerance in OCD - Stephanie J. Grimaldi, and Emily R. Stern * 12. Scrupulosity and Slowness in OCD: Perfectionism as a Central Mechanism - Rachel Ojserkis and Dean McKay * 13. Variable Insight in OCD - Rebecca J. Hamblin, Jennifer Moonjung Park, Monica S. Wu, and Eric A. Storch * 14. Clinical Rating Scales for OCD - Joseph F. McGuire, Eric A. Storch, and Wayne Goodman * 15. Neuropsychosocial Function in OCD - Amitai Abramovitch * 16. Habits and Goals in OCD - Claire M. Gillan * 17. Intolerance of Uncertainty in Obsessive-Compulsive Disorder - Ryan J. Jacoby and Jonathan S. Abramowitz * 18. Pathological responsibility, thought-action fusion, and thought control in OCD - Christine Purdon * Section 3: Biological Underpinnings * 19. Genetics Of OCD - Paul Arnold * 20. Neurocircuitry underlying OCD : neural networks underlying reward and action selection - Suzanne N. Haber * 21. A review and synthesis of functional neuroimaging studies of OCD - Brian P. Brennan and Scott L. Rauch * 22. Functional Imaging Studies of OCD: A Hypothesis-Driven Review - M.M. Vaghi and T.W. Robbins * 23. The Structure of the OCD Brain - Premika S.W. Boedhoe and Odile A. van den Heuvel * 24. Brain Functional Connectivity in OCD - Carles Soriano-Mas and Ben J. Harrison * 25. Neurotransmitter dysregulation in OCD - Ilse Graat, Martijn Figee, and Damiaan Denys * 26. Neuropeptides in OCD - Anahid Kabasakalian, Eric Hollander * 27. Influence of sex hormones on OCD - Valeria Guglielmi, Judith Souget, Wouter van Elzelingen, Ingo Willuhn, and Nienke Vulink * 28. PANDAS as a Post-Streptococcal Autoimmune Neuropsychiatric Form of OCD - Susan E. Swedo, Kyle A. Wiliams * Section 4: Animal Studies * 29. Animal models of OCD: A conceptual framework - Christopher Pittenger, Stephanie Dulawa, and Summer L. Thompson * 30. Extinction of conditioned fear and avoidance: Relevance for OCD - Jose Rodriguez-Romaguera and Gregory J. Quirk * 31. OCD as a failure to integrate goal-directed and habitual action control - Laura Bradfield, Richard Morris, and Bernard W. Balleine * 32. Spontaneously Occurring Animal Models of OCD - Nicholas H. Dodman and Louis Shuster * 33. Mutant Mouse Models of OCD - Louis Y. Tee and Guoping Feng * 34. Targeted circuit manipulations in the modeling of OCD - Susanne E. Ahmari * 35. Pharmacological and behavioral rodent models of OCD - Summer L. Thompson and Stephanie C. Dulawa * Section 5: Treatment * 36. Overview of the treatment of OCD - H. Blair Simpson * 37. Exposure and Response Prevention in OCD - Jonathan S. Abramowitz * 38. Cognitive Therapy for OCD - Maureen Whittal * 39. Mindfulness and Acceptance Therapies for Obsessive-Compulsive and Related Disorders - Kate L. Morrison, Brooke M. Smith, and Michael P. Twohig * 40. Standard Evidence-Based Pharmacological Treatment for OCD - Jemma E. Reid, Samar Reghunandanan, Ann Roberts, and Naomi A. Fineberg * 41. The pharmacological treatment of refractory OCD - Christopher Pittenger * 42. Treatment of Pediatric OCD - S. Evelyn Stewart and Clare Bleakley * 43. Family accommodation in OCD: Prevalence, impact, and clinical implications - Kristin Koller and Eli R. Lebowitz * 44. Nutraceutical and alternative treatments for Obsessive compulsive and Related Disorders - David Camfield and Jerome Sarris * 45. Functional Neurosurgery in Severe and Treatment-Refractory OCD - Erica C. Keen, Alik S. Widge, and Darin D. Dougherty * 46. Deep Brain Stimulation for Intractable OCD - Wayne K. Goodman, Nigel Kennedy, Kyle Lapidus, and Brian H. Kopell * 47. Intensive Treatment Approaches for OCD - Joshua M. Nadeau, Bradley C. Riemann, and Eric Storch * Section 6: OCD-Related Disorders * 48. Obsessive-Compulsive and Related Disorders: A New Category in DSM-5 - Katharine A. Phillips * 49. Clinical Features, Assessment, and Treatment of body Dysmorphic Disorder - Lisa Zakhary, Hilary Weingarden, Alexandra Sullivan, and Sabine Wilhelm * 50. Body Dysmorphic Disorder: Neurobiology and Genetics - Jamie D. Feusner and Danyale McCurdy-McKinnon * 51. Trichtillomania and skin picking disorder - Jon E. Grant, Sarah A. Redden, Eric W. Leppink * 52. Hoarding Disorder: Clinical presentation and treatment - Randy O. Frost, Lucy Graves, Elizabeth Atkins * 53. Comorbidity in Pediatric OCD: Tourette Syndrom - Michael H. Bloch * Section 7. Comorbidity * 54. Mood and Anxiety Disorder Comorbidity in OCD - L. Baer, A. Fang, N.C. Berman, and W.E. Minichiello * 55. Psychological Trauma Exposure and Obsessive-Compulsive symptoms - Dean McKay and Rachel Ojserkis * 56. Eating Disorder Comorbidity with OCD - Marina Gershkovich, Olivia Pasucci, and Joanna Steinglass * 57. Obsessive-Compulsive Symptoms in Schizophrenia: Clinical features, neurobiological correlates and treatment - Michael Poyurovsky * 58. Differentiating Autism Spectrum disorder and OCD - Robert E. Accordino, W. Philip Bartel, Isobel W. Green, Christen L. Kidd, and Christopher J. McDougle * 59. Personality Pathology in OCD: Comorbidity and Contrast with OCPD and Other Personality Disorders - Michael G. Wheaton and Anthony Pinto * Section 8: Special Topics * 60. Etiological models of OCD: anxiety, obsession, compulsion, completeness - Christopher Pittenger, Patricia Gruner, Thomas A. Adams, Benjamin Kelmendi * 61. Evolutionary Perspectives of OCD - Gerrit I. van Schalkwyk and James F. Leckman * 62. Research Domain Criteria and OCD: An oxymoron? - Eyal Kalanthroff, Gideon E. Anholt, and Helen Blair Simpson * 63. OCD in Ethnoracial Minorities: Symptoms, barriers to care, and cultural considerations for treatment - Monnica T. Williams and Terence Ching * 64. OCD in the Educational Setting - Allen H. Weg * 65. The integration of new technological approaches in OCD care - Seth Feuerstein * 66. OCD, Advocacy, and Addressing Stigma - Jeff Szymanski, Carly Bourne * 67. Living with OCD - Elizabeth McIngvale
* 1. Introduction: Narratives of OCD - Elias Aboujaoude and Christopher Pittenger * Section 1: Clinical Presentation and Diagnosis * 2. Clinical Presentation of OCD - Fred Penzel * 3. Pediatric OCD: Clinical Course, Phenomology, and Assessment - Rachel E. Ginsberg, Samantha Morrison, and Anthony Puliafico * 4. Epidemiology, Comorbidity, and Burden of OCD - Albina R. Torres, Leonardo F. Fontenelle, Roseli G. Shavitt, Marcelo Q. Hoexter, Christopher Pittenger, and Euripedes C. Miguel * 5. Natural History and Long-Term Outcome of OCD - Michael H. Bloch * 6. Quality of Life and Psychosocial Functioning in OCD - Christina L. Boisseau, Carly M. Schwartzman, and Steven A. Rasmussen * 7. Psychodynamic perspectives on OCD - Robert A. King * Section 2: Phenomenology and Cognitive Psychology * 8. Symptom heterogeneity in OCD: A dimensional approach - Maria Concei Conceição do Rosário, Marcelo Batistutto, and Ygor Ferrao * 9. Incompleteness and harm avoidance - Stefano Pallanti, Jennifer Barnes, Christopher Pittenger, and Jane Eisen * 10. Disgust and OCD - Lauren Mancusi and Dean McKay * 11. Sensory Processing and Intolerance in OCD - Stephanie J. Grimaldi, and Emily R. Stern * 12. Scrupulosity and Slowness in OCD: Perfectionism as a Central Mechanism - Rachel Ojserkis and Dean McKay * 13. Variable Insight in OCD - Rebecca J. Hamblin, Jennifer Moonjung Park, Monica S. Wu, and Eric A. Storch * 14. Clinical Rating Scales for OCD - Joseph F. McGuire, Eric A. Storch, and Wayne Goodman * 15. Neuropsychosocial Function in OCD - Amitai Abramovitch * 16. Habits and Goals in OCD - Claire M. Gillan * 17. Intolerance of Uncertainty in Obsessive-Compulsive Disorder - Ryan J. Jacoby and Jonathan S. Abramowitz * 18. Pathological responsibility, thought-action fusion, and thought control in OCD - Christine Purdon * Section 3: Biological Underpinnings * 19. Genetics Of OCD - Paul Arnold * 20. Neurocircuitry underlying OCD : neural networks underlying reward and action selection - Suzanne N. Haber * 21. A review and synthesis of functional neuroimaging studies of OCD - Brian P. Brennan and Scott L. Rauch * 22. Functional Imaging Studies of OCD: A Hypothesis-Driven Review - M.M. Vaghi and T.W. Robbins * 23. The Structure of the OCD Brain - Premika S.W. Boedhoe and Odile A. van den Heuvel * 24. Brain Functional Connectivity in OCD - Carles Soriano-Mas and Ben J. Harrison * 25. Neurotransmitter dysregulation in OCD - Ilse Graat, Martijn Figee, and Damiaan Denys * 26. Neuropeptides in OCD - Anahid Kabasakalian, Eric Hollander * 27. Influence of sex hormones on OCD - Valeria Guglielmi, Judith Souget, Wouter van Elzelingen, Ingo Willuhn, and Nienke Vulink * 28. PANDAS as a Post-Streptococcal Autoimmune Neuropsychiatric Form of OCD - Susan E. Swedo, Kyle A. Wiliams * Section 4: Animal Studies * 29. Animal models of OCD: A conceptual framework - Christopher Pittenger, Stephanie Dulawa, and Summer L. Thompson * 30. Extinction of conditioned fear and avoidance: Relevance for OCD - Jose Rodriguez-Romaguera and Gregory J. Quirk * 31. OCD as a failure to integrate goal-directed and habitual action control - Laura Bradfield, Richard Morris, and Bernard W. Balleine * 32. Spontaneously Occurring Animal Models of OCD - Nicholas H. Dodman and Louis Shuster * 33. Mutant Mouse Models of OCD - Louis Y. Tee and Guoping Feng * 34. Targeted circuit manipulations in the modeling of OCD - Susanne E. Ahmari * 35. Pharmacological and behavioral rodent models of OCD - Summer L. Thompson and Stephanie C. Dulawa * Section 5: Treatment * 36. Overview of the treatment of OCD - H. Blair Simpson * 37. Exposure and Response Prevention in OCD - Jonathan S. Abramowitz * 38. Cognitive Therapy for OCD - Maureen Whittal * 39. Mindfulness and Acceptance Therapies for Obsessive-Compulsive and Related Disorders - Kate L. Morrison, Brooke M. Smith, and Michael P. Twohig * 40. Standard Evidence-Based Pharmacological Treatment for OCD - Jemma E. Reid, Samar Reghunandanan, Ann Roberts, and Naomi A. Fineberg * 41. The pharmacological treatment of refractory OCD - Christopher Pittenger * 42. Treatment of Pediatric OCD - S. Evelyn Stewart and Clare Bleakley * 43. Family accommodation in OCD: Prevalence, impact, and clinical implications - Kristin Koller and Eli R. Lebowitz * 44. Nutraceutical and alternative treatments for Obsessive compulsive and Related Disorders - David Camfield and Jerome Sarris * 45. Functional Neurosurgery in Severe and Treatment-Refractory OCD - Erica C. Keen, Alik S. Widge, and Darin D. Dougherty * 46. Deep Brain Stimulation for Intractable OCD - Wayne K. Goodman, Nigel Kennedy, Kyle Lapidus, and Brian H. Kopell * 47. Intensive Treatment Approaches for OCD - Joshua M. Nadeau, Bradley C. Riemann, and Eric Storch * Section 6: OCD-Related Disorders * 48. Obsessive-Compulsive and Related Disorders: A New Category in DSM-5 - Katharine A. Phillips * 49. Clinical Features, Assessment, and Treatment of body Dysmorphic Disorder - Lisa Zakhary, Hilary Weingarden, Alexandra Sullivan, and Sabine Wilhelm * 50. Body Dysmorphic Disorder: Neurobiology and Genetics - Jamie D. Feusner and Danyale McCurdy-McKinnon * 51. Trichtillomania and skin picking disorder - Jon E. Grant, Sarah A. Redden, Eric W. Leppink * 52. Hoarding Disorder: Clinical presentation and treatment - Randy O. Frost, Lucy Graves, Elizabeth Atkins * 53. Comorbidity in Pediatric OCD: Tourette Syndrom - Michael H. Bloch * Section 7. Comorbidity * 54. Mood and Anxiety Disorder Comorbidity in OCD - L. Baer, A. Fang, N.C. Berman, and W.E. Minichiello * 55. Psychological Trauma Exposure and Obsessive-Compulsive symptoms - Dean McKay and Rachel Ojserkis * 56. Eating Disorder Comorbidity with OCD - Marina Gershkovich, Olivia Pasucci, and Joanna Steinglass * 57. Obsessive-Compulsive Symptoms in Schizophrenia: Clinical features, neurobiological correlates and treatment - Michael Poyurovsky * 58. Differentiating Autism Spectrum disorder and OCD - Robert E. Accordino, W. Philip Bartel, Isobel W. Green, Christen L. Kidd, and Christopher J. McDougle * 59. Personality Pathology in OCD: Comorbidity and Contrast with OCPD and Other Personality Disorders - Michael G. Wheaton and Anthony Pinto * Section 8: Special Topics * 60. Etiological models of OCD: anxiety, obsession, compulsion, completeness - Christopher Pittenger, Patricia Gruner, Thomas A. Adams, Benjamin Kelmendi * 61. Evolutionary Perspectives of OCD - Gerrit I. van Schalkwyk and James F. Leckman * 62. Research Domain Criteria and OCD: An oxymoron? - Eyal Kalanthroff, Gideon E. Anholt, and Helen Blair Simpson * 63. OCD in Ethnoracial Minorities: Symptoms, barriers to care, and cultural considerations for treatment - Monnica T. Williams and Terence Ching * 64. OCD in the Educational Setting - Allen H. Weg * 65. The integration of new technological approaches in OCD care - Seth Feuerstein * 66. OCD, Advocacy, and Addressing Stigma - Jeff Szymanski, Carly Bourne * 67. Living with OCD - Elizabeth McIngvale
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