Karol Grela

Olefin Metathesis (eBook, PDF)

Theory and Practice

• Format: PDF

Produktbeschreibung

This is a complete examination of the theory and methods of modern olefin metathesis, one of the most widely used chemical reactions in research and industry. * Provides basic information for non-specialists, while also explaining the latest trends and advancements in the field to experts * Discusses the various types of metathesis reactions, including CM, RCM, enyne metathesis, ROMP, and tandem processes, as well as their common applications * Outlines the tools of the trade--from the important classes of active metal complexes to optimal reaction conditions--and suggests practical solutions for common reaction problems * Includes tables with structures of commercial catalysts, and recommendations for commercial catalyst suppliers

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Produktdetails

• Verlag: John Wiley & Sons
• Seitenzahl: 608
• Erscheinungstermin: 7. April 2014
• Englisch
• ISBN-13: 9781118711705
• Artikelnr.: 40781606

Autorenporträt

KAROL GRELA is a Professor at the Institute of Organic Chemistry, Polish Academy of Sciences, and the Director of the Organometallic Synthesis Laboratory at the Biological and Chemical Research Centre of the Faculty of Chemistry, University of Warsaw, Poland. Having written over 100 peer-reviewed papers, he is on the editorial board of Chemistry--a European Journal and on the advisory board for the European Journal of Organic Chemistry and Organometallics.

Inhaltsangabe

PREFACE ix

CONTRIBUTORS xi

PART I APPLICATIONS OF OLEFIN METATHESIS REACTIONS 1

Section I INTRODUCTION 3

1 Olefin Metathesis Reactions: From a Historical Account toRecent Trends 5
Didier Astruc

Section II TYPES OF OLEFIN METATHESIS REACTIONS 37

2 Cross Metathesis 39
Karolina Zukowska and Karol Grela

3 Ring-Closing Metathesis 85
Bianca J. van Lierop, Justin A. M. Lummiss, and Deryn E.Fogg

4 Ene-Yne Metathesis 153
Steven T. Diver and Justin R. Griffiths

5 Domino and Other Olefin Metathesis Reaction Sequences187
Bernd Schmidt and Stefan Krehl

6 Enantioselective Olefin Metathesis 233
Brice Stenne and Shawn K. Collins

7 Olefin Metathesis Polymerization 269
Astrid-Caroline Knall and Christian Slugovc

Section III APPLICATIONS OF OLEFIN METATHESIS REACTIONS285

8 Applications in the Synthesis of Natural and BiologicallyActive Molecules 287
Janine Cossy

9 Multifold Ring-Closing Olefin Metatheses in Syntheses ofOrganometallic Molecules with Unusual Connectivities 311
Tobias Fiedler and John A. Gladysz

10 Industrial Applications of Olefin Metathesis Polymerization329
Christian Slugovc

11 Commercial Potential of Olefin Metathesis of RenewableFeedstocks 335
Andrew Nickel and Richard L. Pederson

12 Challenges and Opportunities for Scaling the Ring-ClosingMetathesis Reaction in the Pharmaceutical Industry 349
Keith R. Fandrick, Jolaine Savoie, Nathan Yee, Jinhua J. Song,and Chris H. Senanayake

PART II DEVELOPMENT OF THE TOOLS 367

Section IV DIFFERENT CLASSES OF OLEFIN METATHESIS CATALYSTS369

13 Well-Defined Olefin Metathesis Catalysts Based on Metals ofGroup 4-7 371
Cezary Pietraszuk

14 Ruthenium-Benzylidene Olefin Metathesis Catalysts 397
Georgios C. Vougioukalakis

15 Ruthenium-Indenylidene and Other Alkylidene Containing OlefinMetathesis Catalysts 417
César A. Urbina-Blanco, Stefano Guidone, Steven P. Nolan,and Catherine S. J. Cazin

16 Hoveyda-Type Olefin Metathesis Complexes 437
Yakov Ginzburg and N. Gabriel Lemcoff

17 Schiff Base Catalysts and Other Related Latent Systems forPolymerization Reactions 453
Yohann Morin and Régis M. Gauvin

Section V DEVELOPMENT OF CONCEPTS IN OLEFIN METATHESISCATALYSTS 473

18 Novel Concepts in Catalyst Design--a Case Study ofDevelopment of Hoveyda-Type Complexes 475
Micha³ Barbasiewicz

19 Theoretical Attempts: "In Silico OlefinMetathesis"--How Can Computers Help in the Understandingof Metathesis Mechanisms and in Catalysts Development? 483
Albert Poater, Laura Falivene, and Luigi Cavallo

20 Immobilization of Olefin Metathesis Catalysts 495
Michael R. Buchmeiser

21 Olefin Metathesis inWater and Aqueous Media 515
Bruce H. Lipshutz and Subir Ghorai

22 Olefin Metathesis in Green Organic Solvents and WithoutSolvent 523
Christian Bruneau and Cédric Fischmeister

23 Olefin Metathesis in Fluorous Phases and in FluorinatedAromatic Solvents 537
Cezary Samoj³owicz, Anna Kajetanowicz, and KarolGrela

24 Olefin Metathesis in Ionic Liquids 547
Pierre Queval, Mathieu Rouen, Annie-Claude Gaumont, IsabelleDez, Olivier Baslé, and Marc Mauduit

25 Purification Strategies in Olefin Metathesis 559
Krzysztof Skowerski and £ukasz Gu³ajski

PART III TABLES AND CHARTS 573

Section VI OLEFIN METATHESIS CATALYSTS--A TABULAR REVIEW575
£ukasz Wo´zniak, Grzegorz Zieli´nski, andKarol Grela

Outlook and Perspectives 587

INDEX 589