Omics in Clinical Practice (eBook, PDF)

Genomics, Pharmacogenomics, Proteomics, and Transcriptomics in Clinical Research
Redaktion: Liu, Yu

• Format: PDF

Produktbeschreibung

This title includes a number of Open Access chapters.This book serves as an introduction to genomics, proteomics, and transcriptomics, putting these fields in relation to human disease and ailments. The various chapters consider the role of translation and personalized medicine, as well as pathogen detection, evolution, and infection, in relation t

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 464
• Erscheinungstermin: 20. Juni 2014
• Englisch
• ISBN-13: 9781482262438
• Artikelnr.: 41213860

Autorenporträt

Dr. Yu Liu is a bioinformatician with special interest in next-gen sequencing and its applications. His specialties are molecular biology, DNA sequence analysis, next-gen sequencing application on gene expression analysis and comparative genomics, and microarray gene expression analysis. He is the director of the Bioinformatics Resource Center at the University of Wisconsin-Madison. He has a master's degree in computer science from the University of Wisconsin-Madison; a master's degree in developmental biology from the Chinese Academy of Science; and PhD in molecular biology from The Ohio State University.

Inhaltsangabe

Introduction. Part 1: Omics and Human Disease. Comparative Mitochondrial
Proteomics: Perspective in Human Diseases. Studies of Complex Biological
Systems with Applications to Molecular Medicine: The Need to Integrate
Transcriptomic and Proteomic Approaches. Next Generation Sequencing in
Cancer Research and Clinical Application. Scientific Challenges and
Implementation Barriers to Translation of Pharmacogenomics in Clinical
Practice. Part 2: Translational and Personalized Medicine. Clinical
Proteomics and Omics Clues Useful in Translational Medicine Research.
Genomes2Drugs: Identifies Target Proteins and Lead Drugs from Proteome Data
. Part 3: Molecular and Genetic Markers. Pitfalls and Limitations in
Translation from Biomarker Discovery to Clinical Utility in Predictive and
Personalised Medicine. How Bioinformatics Influences Health Informatics:
Usage of Biomolecular Sequences, Expression Profiles and Automated
Microscopic Image Analyses for Clinical Needs and Public Health.
Application of "Omics" to Prion Biomarker Discovery. Part 4: Omics and
Pathogens. Insights from Genomics into Bacterial Pathogen Populations.
High Throughput Sequencing and Proteomics to Identify Immunogenic Proteins
of a New Pathogen: The Dirty Genome Approach. Coronavirus Genomics and
Bioinformatics Analysis. Part 5: Companion Diagnostics. Applications of
Next-Generation Sequencing Technologies to Diagnostic Virology. Mass
Spectrometry-Based Proteomics in Molecular Diagnostics: Discovery of Cancer
Biomarkers Using Tissue Culture. Index.