eBook, PDF

Opiate Receptors and Antagonists (eBook, PDF)

From Bench to Clinic

Redaktion: Dean, Reginald; Negus, S. Stevens; Bilsky, Edward J.

Beschreibung

The evolution in our understanding of Opioid receptors and their subtypes is intimately linked to the development of new pharmacological treatments for diseases and disorders as diverse as addiction, self-injurious behavior, pain, cancer, inflammation, eating disorders, traumatic injury, pruritis and movement disorders. The contributions contained in Opioid Receptors and Antagonists: From Bench to Clinic represent efforts from leading international scientists and clinicians making use of the latest information emerging from the study of the opioid-receptor system. The authors use a variety of experimental and clinical approaches involving the fields of molecular biology, biochemistry, anatomy, pharmacology, behavioral neuroscience and psychiatry to illustrate rapidly developing experimental and therapeutic areas. Highlights include characterization of opioid receptors, chemistry and pharmacology of opiod antagonists for various receptor subtypes (Mu, Kappa, and Delta), discussion of therapeutic uses of opiod antagonists and exploration of innovative approaches to therapeutic drug delivery.

Opioid Receptors and Antagonists: From Bench to Clinic offers a comprehensive view of recent work on opiod antagonist applications and uses in various clinical treatments. Emphasis is placed on disorders of the reward system. This volume serves as reference while also illuminating prospects for future research.

Technische Details

• Geräte: PC
• ohne Kopierschutz
• Größe: 8.94MB

Barrierefreiheit

• Text-to-Speech

Produktdetails

• Verlag: Humana Press
• Seitenzahl: 757
• Erscheinungstermin: 12. März 2009
• Englisch
• ISBN-13: 9781597451970
• Artikelnr.: 37338870

Rezensionen

From the reviews:

"The authors do an excellent job of providing insight into the background of the many factors related to opioid receptor antagonists. ... Overall, this work is a well written and interesting text and would be a very useful addition to the personal libraries of those medicinal chemists with a research interest in the modulation of the opioid receptor system." (Thomas E. Prisinzano, Journal of Medicinal Chemistry, Vol. 53 (2), March, 2010)

"This book is focused on the therapeutic uses of opioid antagonists ranging from classical opioid antagonists to novel chemical entities. In any therapeutic field examined, the aim of book as outlined by the title-'From Bench to Clinic'-is achieved. ... The clinical applications of opioid antagonists are extensively discussed in almost all chapters of this book ... . In conclusion, this book gives an interesting analysis of the different fields of knowledge and research concerning therapeutic uses of opioid antagonists in recent years." (Agostino Marrazzo, ChemBioChem, Vol. 5, 2010)