Frank Vollmer, Deshui Yu

Optical Whispering Gallery Modes for Biosensing (eBook, ePUB)

From Physical Principles to Applications

• Format: ePub

Produktbeschreibung

This interdisciplinary book covers the fundamentals of optical whispering gallery mode (WGM) microcavities, light-matter interaction, and biomolecular structure with a focus on applications in biosensing. Novel biosensors based on the hybridization of WGM microcavities and localized surface plasmon resonances (LSPRs) in metal nanoparticles have emerged as the most sensitive microsystem biodetection technology that boasts single molecule detection capability without the need for amplification and labeling of the analyte. The book provides an ample survey of the physical mechanisms of WGMs and LSPRs for detecting affinity, concentration, size, shape and orientation of biomarkers, while informing the reader about different classes of biomolecules, their optical properties and their importance in label-free clinical diagnostics. For the more advanced reader, advanced applications of WGMs and LSPRs in exploring the fundamental nature of quantum physics are discussed.

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Produktdetails

• Verlag: Springer International Publishing
• Seitenzahl: 416
• Erscheinungstermin: 16. Oktober 2020
• Englisch
• ISBN-13: 9783030602352
• Artikelnr.: 61344189

Autorenporträt

Frank Vollmer is Professor in Biophysics at the University of Exeter, UK. He obtained his PhD in physics and biology from the Rockefeller University in NYC, USA, in 2004. He was Rowland Fellow at Harvard University from 2004 to 2009, Scholar-in-Residence at the Wyss Institute at Harvard in 2010, Group Leader (untenured Associate Professor) at the Max Planck Institute for the Science of Light in Germany from 2011-2016 and Instructor in Medicine at Brigham and Women's Hospital/Harvard Medical School where he directed a satellite laboratory from 2011-2016. Since 2016 he is Professor in Biophysics at the School of Physics, University of Exeter, UK. He received the Royal Society Wolfson Research Merit Award in 2017 and in 2021 the Rosalind Franklin Medal and Prize from the Institute of Physics (IoP). Since 2021 he is Fellow of the IoP. Deshui Yu is Research Fellow at the University of Exeter. He received his B.Eng. degree in electronic science andtechnology from the Shandong University, China, in 2004 and PhD in radio physics from the Peking University, China, in 2009. He subsequently worked as a postdoctoral research fellow at the University of Tokyo from 2009 to 2012, the University of Nottingham from 2013 to 2014, and the National University of Singapore from 2015 to 2018. Currently, he is a postdoctoral researcher at the University of Exeter since 2019. His research mainly focuses on the quantum optics theory in quantum metrology and sensing and superconducting quantum circuits.

Inhaltsangabe

Sensing with Light.- Surface Plasmon Resonance.- Whispering Gallery Modes in Optical Microcavities.- Applications of WGM Microcavities in Physics.- Single Molecule Sensing.- Fundamentals of Quantum Optics.- Molecular cavity QED.